Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/9122
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dc.contributor.authorYardımcı, Atike İnce-
dc.contributor.authorAypek, Hande-
dc.contributor.authorÖztürk, Özgür-
dc.contributor.authorYılmaz, Selahattin-
dc.contributor.authorÖzçivici, Engin-
dc.contributor.authorMeşe, Gülistan-
dc.contributor.authorSelamet, Yusuf-
dc.date.accessioned2020-07-25T22:03:49Z-
dc.date.available2020-07-25T22:03:49Z-
dc.date.issued2019-
dc.identifier.issn2296-9837-
dc.identifier.issn2296-9845-
dc.identifier.urihttps://doi.org/10.4028/www.scientific.net/JBBBE.41.69-
dc.identifier.urihttps://hdl.handle.net/11147/9122-
dc.descriptionWOS: 000465412300006en_US
dc.description.abstractPolypyrrole (PPy) is an attractive scaffold material for tissue engineering with its non-toxic and electrically conductive properties. There has not been enough information about PPy usage in skin tissue engineering. The aim of this study is to investigate biocompatibility of polyacrilonitrile (PAN)/PPy nanofibrous scaffold for human keratinocytes. PAN/PPy bicomponent nanofibers were prepared by electrospinning, in various PPy concentrations and with carbon nanotube (CNT) incorporation. The average diameter of electrospun nanofibers decreased with increasing PPy concentration. Further, agglomerated CNTs caused beads and disordered parts on the surface of nanofibers. Biocompatibility of these PAN/PPy and PAN/PPy/CNT scaffolds were analyzed in vitro. Both scaffolds provided adhesion and proliferation of keratinocytes. Nanofiber diameter did not significantly influence the morphology of cells. However, with increasing number of cells, cells stayed among nanofibers and this affected their shape and size. In this study, we demonstrated that PAN/PPy and PAN/PPy/CNT scaffolds enabled the growth of keratinocytes, showing their biocompatibility.en_US
dc.language.isoenen_US
dc.publisherTrans Tech Publicationsen_US
dc.relation.ispartofJournal of Biomimetics Biomaterials and Biomedical Engineeringen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPolypyrroleen_US
dc.subjectcarbon nanotube (CNT)en_US
dc.subjectelectrospinningen_US
dc.subjectbiocompatibilityen_US
dc.subjectkeratinocyteen_US
dc.titleCNT Incorporated Polyacrilonitrile/Polypyrrole Nanofibers as Keratinocytes Scaffolden_US
dc.typeArticleen_US
dc.institutionauthorYardımcı, Atike İnce-
dc.institutionauthorAypek, Hande-
dc.institutionauthorÖztürk, Özgür-
dc.institutionauthorYılmaz, Selahattin-
dc.institutionauthorÖzçivici, Engin-
dc.institutionauthorMeşe, Gülistan-
dc.institutionauthorSelamet, Yusuf-
dc.departmentIzmir Institute of Technology. Materials Science and Engineeringen_US
dc.departmentIzmir Institute of Technology. Molecular Biology and Geneticsen_US
dc.departmentIzmir Institute of Technology. Chemical Engineeringen_US
dc.departmentIzmir Institute of Technology. Biotechnology and Bioengineeringen_US
dc.identifier.volume41en_US
dc.identifier.startpage69en_US
dc.identifier.endpage81en_US
dc.identifier.wosWOS:000465412300006en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.4028/www.scientific.net/JBBBE.41.69-
dc.relation.doi10.4028/www.scientific.net/JBBBE.41.69en_US
dc.coverage.doi10.4028/www.scientific.net/JBBBE.41.69en_US
dc.identifier.scopusqualityQ4-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairetypeArticle-
item.languageiso639-1en-
crisitem.author.dept03.02. Department of Chemical Engineering-
crisitem.author.dept03.01. Department of Bioengineering-
crisitem.author.dept04.03. Department of Molecular Biology and Genetics-
Appears in Collections:WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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