• Secreted Wnt antagonists in leukemia: A road yet to be paved 

  Pehlivan, Melek; Çalışkan, Ceyda; Yüce, Zeynep; Sercan, Hakkı Ogün (Elsevier, 2018-06)

  Wnt signaling has been a topic of research for many years for its diverse and fundamental functions in physiological (such as embryogenesis, organogenesis, proliferation, tissue repair and cellular differentiation) and ...

• Genome-wide association mapping of yield components and drought tolerance-related traits in cotton 

  Akköse Baytar, Asena; Peynircioğlu, Ceng; Sezener, Volkan; Başal, Hüseyin; Frary, Anne; Frary, Amy; Doğanlar, Sami (Springer, 2018-06)

  Drought causes serious yield losses in cotton production throughout the world. Association mapping allows identification and localization of the genes controlling drought-related traits which will be helpful in cotton ...

• Transcriptomic analysis of boron hyperaccumulation mechanisms in Puccinellia distans 

  Öztürk, Saniye Elvan; Göktay, Mehmet; Has, Canan; Babaoğlu, Mehmet; Allmer, Jens; Doğanlar, Sami; Frary, Anne (Elsevier, 2018-05)

  Puccinellia distans, common alkali grass, is found throughout the world and can survive in soils with boron concentrations that are lethal for other plant species. Indeed, P. distans accumulates very high levels of this ...

• An answer to colon cancer treatment by mesenchymal stem cell originated from adipose tissue 

  İplik, Elif Sinem; ERtuğrul, Barış; Kozanoğlu, İlknur; Baran, Yusuf (Mashhad University of Medical Sciences, 2018-05)

  Objective(s): Colon cancer is risen up with its complex mechanism that directly impacts on its treatment as well as its common prevalence. Mesenchymal stem cells (MSCs) have been considered as a therapeutic candidate for ...

• Sensitive and specific detection of ligands using engineered riboswitches 

  Morse, Daniel P.; Nevins, Colin E.; Aggrey-Fynn, Joana Efua; Bravo, Rick J.; Pfaeffle, Herman O.I.; Laney, Jess E. (Elsevier, 2018-04)

  Riboswitches are RNA elements found in non-coding regions of messenger RNAs that regulate gene expression through a ligand-triggered conformational change. Riboswitches typically bind tightly and specifically to their ...

• Murine Sialidase Neu3 facilitates GM2 degradation and bypass in mouse model of Tay-Sachs disease 

  Seyrantepe, Volkan; Akyıldız Demir, Seçil; Timur, Zehra Kevser; Von Gerichten, Johanna; Marsching, Christian; Erdemli, Esra; Öztaş, Emin; Takahashi, Kohta; Yamaguchi, Kazunori; Ateş, Nurselin; Dönmez Demir, Buket; Dalkara, Turgay; Erich, Katrin; Hopf, Carsten; Sandhoff, Roger; Miyagi, Taeko (Elsevier, 2018-01)

  Tay-Sachs disease is a severe lysosomal storage disorder caused by mutations in Hexa, the gene that encodes for the α subunit of lysosomal β-hexosaminidase A (HEXA), which converts GM2 to GM3 ganglioside. Unexpectedly, ...

• Determining the C-terminal amino acid of a peptide from MS/MS data 

  Allmer, Jens (Proteomass Scientific Society, 2013-12)

  Proteomics is currently chiefly based on mass spectrometry (MS) which is the tool of choice to investigate proteins. Two computational approaches to derive the tandem mass spectrum precursor’s sequence are widely employed. ...

• Nanocarriers for plant-derived natural compounds 

  Bayraktar, Oğuz; Erdoğan, İpek; Köse, Merve D.; Kalmaz, Gülcan (Elsevier, 2017-05)

  Natural products constitute a large fraction in drug discovery processes. The term includes compounds from plants, microorganisms, and animals. Most of the natural products are secondary metabolites derived from plants, ...

• Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin 

  Coşacak, Mehmet İlyas; Erdoğan, İpek; Nalbant, Ayten; Akgül, Bünyamin (Elsevier, 2018-04)

  In this article, we report a small RNA data set obtained from human T cell acute leukemia Jurkat cells, which were treated with the universal apoptotic agent camptothecin. Based on the Annexin-V labeling pattern, we sorted ...

• Re-arrangements in the cytoplasmic distribution of small RNAs following the maternal-to-zygotic transition in Drosophila embryos 

  Coşacak, Mehmet İlyas; Yiğit, Hatice; Kızıl, Çağhan; Akgül, Bünyamin (MDPI, 2018-02)

  Small ribonucleic acids (RNAs) are known to regulate gene expression during early development. However, the dynamics of interaction between small RNAs and polysomes during this process is largely unknown. To investigate ...

• The expressed MicroRNA-mRNA interactions of Toxoplasma gondii 

  Acar, İlhan Erkin; Saçar Demirci, Müşerref Duygu; Groß, Uwe; Allmer, Jens (Frontiers Media S.A., 2018-01)

  MicroRNAs (miRNAs) are involved in post-transcriptional modulation of gene expression and thereby have a large influence on the resulting phenotype. We have previously shown that miRNAs may be involved in the communication ...

• Deep sequencing reveals two Jurkat subpopulations with distinct miRNA profiles during camptothecin-induced apoptosis 

  Erdoğan, İpek; Coşacak, Mehmet İlyas; Nalbant, Ayten; Akgül, Bünyamin (TUBITAK, 2018)

  MicroRNAs (miRNAs) are small noncoding RNAs of about 19-25 nt that regulate gene expression posttranscriptionally under various cellular conditions, including apoptosis. The miRNAs involved in modulation of apoptotic events ...

• The importance of boron in biological systems 

  Uluışık, İrem; Karakaya, Hüseyin Çağlar; Koç, Ahmet (Elsevier, 2018-01)

  Boron is an essential element for plants and probably essential for human and animal health. Boron has a broad range of physiological effects on biological systems at low concentrations, whereas it is toxic to at high ...

• Biofabrication of in situ self assembled 3D cell cultures in a weightlessness environment generated using magnetic levitation 

  Anıl İnevi, Müge; Yaman, Sena; Arslan Yıldız, Ahu; Meşe, Gülistan; Yalçın Özuysal, Özden; Tekin, Hüseyin Cumhur; Özçivici, Engin (Nature Publishing, 2018-12)

  Magnetic levitation though negative magnetophoresis is a novel technology to simulate weightlessness and has recently found applications in material and biological sciences. Yet little is known about the ability of the ...

• Cell proliferation and cytotoxicity assays 

  Adan, Aysun; Kiraz, Yağmur; Baran, Yusuf (Bentham Science, 2016-11)

  Cell viability is defined as the number of healthy cells in a sample and proliferation of cells is a vital indicator for understanding the mechanisms in action of certain genes, proteins and pathways involved cell survival ...

• The second case of saposin a deficiency and altered autophagy 

  Köse, Melis; Akyıldız Demir, Seçil; Akıncı, Gülçin; Eraslan, Cenk; Yılmaz, Ünsal; Ceylaner, Serdar; Sözmen Yıldırım, Eser; Seyrantepe, Volkan (Springer, 2018)

  Krabbe disease is a lysosomal storage disease caused by galactosylceramidase deficiency, resulting in neurodegeneration with a rapid clinical downhill course within the first months of life in the classic infantile ...

• Determination of the effects of biomaterials on human peripheral blood mononuclear cells (PBMC) 

  Sudağıdan, Mert; Güneş, Hatice; Harsa, Şebnem (European IOS Press, 2002)

• Cellular distribution of invadopodia is regulated by nanometer scale surface protein patterns 

  Batı Ayaz, Gizem; Can, Ali; Pesen Okvur, Devrim (Elsevier, 2017-10)

  Invadopodia are proteolytic structures formed by cancer cells. It is not known whether their cellular distribution can be regulated by the organization of the extracellular matrix or the organization of the golgi complex ...

• Environmentally responsive dual-targeting nanoparticles: Improving drug accumulation in cancer cells as a way of preventing anticancer drug efflux 

  Dağlıoğlu, Cenk (American Pharmacists Association, 2018-03)

  Drug targeting and stimuli-responsive drug release are 2 active areas of cancer research and hold tremendous potential in the management of cancer drug resistance. In this study, I addressed this issue and focused on the ...

• Plant-microbe interactions in phytoremediation 

  Özyiğit, İbrahim İlker; Doğan, İlhan (Elsevier, 2014)

  Our atmosphere, water resources and soil are becoming increasingly contaminated with inorganic and organic compounds as a result of anthropogenic-driven inputs, mainly from industry, mining, motorized traffic, agriculture, ...

View more