Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/2810
Title: Genome-wide identification of genes that play a role in boron stress response in yeast
Authors: Uluışık, İrem
Kaya, Alaattin
Ünlü, Ercan Selçuk
Avşar, Kadir
Karakaya, Hüseyin Çağlar
Yalçın, Talat
Koç, Ahmet
Uluışık, İrem
Kaya, Alaattin
Ünlü, Ercan Selçuk
Avşar, Kadir
Karakaya, Hüseyin Çağlar
Yalçın, Talat
Koç, Ahmet
Izmir Institute of Technology. Molecular Biology and Genetics
Keywords: Boron
Boric acid
Yeast
Genomics
Proteomics
Issue Date: Feb-2011
Publisher: Elsevier Ltd.
Source: Uluışık, İ., Kaya, A., Ünlü, E. S., Avşar, K., Karakaya, H. C., Yalçın, T., and Koç, A. (2011). Genome-wide identification of genes that play a role in boron stress response in yeast. Genomics, 97 (2),106-111. doi:10.1016/j.ygeno.2010.10.006
Abstract: Boron is an essential micronutrient for plants and it is either necessary or beneficial for animals. Studies identified only few genes related to boron metabolism thus far and details of how boron is imported into cells and used in cell metabolism are largely unknown. In order to identify genes that play roles in boron metabolism, we screened the entire set of yeast haploid deletion mutants and identified 6 mutants that were resistant to toxic levels of boron, and 21 mutants that were highly sensitive to boron treatment. Furthermore, we performed a proteomic approach to identify additional proteins that are significantly up-regulated by boron treatment. Our results revealed many genes and pathways related to boron stress response and suggest a possible link between boron toxicity and translational control.
URI: http://doi.org/10.1016/j.ygeno.2010.10.006
http://hdl.handle.net/11147/2810
ISSN: 0888-7543
0888-7543
Appears in Collections:Chemistry / Kimya
Molecular Biology and Genetics / Moleküler Biyoloji ve Genetik
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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