• Cytotoxic tolerance of healthy and cancerous bone cells to anti-microbial phenolic compounds depend on culture conditions 

  Karadaş, Özge; Meşe, Gülistan; Özçivici, Engin (Springer, 2019)

  Carnosol and carnosic acid are polyphenolic compounds found in rosemary and sage with known anti-oxidant, anti-inflammatory, and anti-microbial properties. Here, we addressed the potential use of carnosol and carnosic acid ...

• Bioactive fish scale incorporated chitosan biocomposite scaffolds for bone tissue engineering 

  Kara, Aylin; Tamburacı, Sedef; Tihmınlıoğlu, Funda; Havıtçıoğlu, Hasan (Elsevier, 2019-07)

  Recently, biologically active natural macromolecules have come into prominence to be used as potential materials in scaffold design due to their unique characteristics which can mimic the human tissue structure with their ...

• Green fabrication of lanthanide-doped hydroxide-based phosphors: Y(OH)(3):Eu3+ nanoparticles for white light generation 

  Guner, Tugrul; Kus, Anilcan; Ozcan, Mehmet; Genc, Aziz; Sahin, Hasan; Demir, Mustafa M. (Beilstein-Institut, 2019)

  Phosphors can serve as color conversion layers to generate white light with varying optical features, including color rendering index (CRI), high correlated color temperature (CCT), and luminous efficacy. However, they are ...

• Polyethers isolated from the marine actinobacterium Streptomyces cacaoi inhibit autophagy and induce apoptosis in cancer cells 

  Khan, Nasar; Yilmaz, Sinem; Aksoy, Semiha; Uzel, Atac; Tosun, Cigdem; Kirmizibayrak, Petek Ballar; Bedir, Erdal (Elsevier Ireland Ltd, 2019)

  Polyether compounds, a large group of biologically active metabolites produced by Streptomyces species have been reported to show a variety of bioactivity such as antibacterial, antifungal, antiparasitic, antiviral, and ...

• Bioactive diatomite and POSS silica cage reinforced chitosan/Na-carboxymethyl cellulose polyelectrolyte scaffolds for hard tissue regeneration 

  Tamburaci, Sedef; Kimna, Ceren; Tihminlioglu, Funda (Elsevier Science Bv, 2019)

  Recently, natural polymers are reinforced with silica particles for hard tissue engineering applications to induce bone regeneration. In this study, as two novel bioactive agents, effects of diatomite and polyhedral ...

• Effects of N-Terminal and C-Terminal Polyhistidine Tag on the Stability and Function of the Thermophilic P450 CYP119 

  Aslantas, Yaprak; Surmeli, Nur Basak (Hindawi Ltd, 2019)

  Biocatalysts are sought-after in synthesis of pharmaceuticals and agrochemicals due to their high regioselectivity and enantioselectivity. Among biocatalysts, heme-containing cytochrome P450 (P450) oxygenases are an ...

• Development of adjuvant nanocarrier systems for seasonal influenza A (H3N2) vaccine based on Astragaloside VII and gum tragacanth (APS) 

  Yakubogullari, Nilgun; Genc, Rukan; Coven, Fethiye; Nalbantsoy, Ayse; Bedir, Erdal (Elsevier Sci Ltd, 2019)

  Adjuvants are chemical/biological substances that are used in vaccines to increase the immunogenicity of antigens. A few adjuvants have been developed for use in human vaccines because of their limitations including lack ...

• Auditory event-related potentials demonstrate early cognitive impairment in children with subclinical hypothyroidism 

  Atli, Sibel Kocaaslan; Dundar, Nihal Olgac; Bayazit, Onur; Esin, Nur Evirgen; Erdogan, Ugras; Catli, Gonul; Dundar, Bumin Nuri (Walter De Gruyter Gmbh, 2019)

  Background: The aim of this study was to examine the cognitive functions of children with subclinical hypothyroidism (SH) and healthy children with the use of auditory event-related potentials (AERPs) and neuropsychological ...

• Osteogenic differentiation of mesenchymal stem cells on random and aligned PAN/PPy nanofibrous scaffolds 

  Yardimci, Atike Ince; Baskan, Oznur; Yilmaz, Selahattin; Mese, Gulistan; Ozcivici, Engin; Selamet, Yusuf (Sage Publications Ltd, 2019)

  The aim of this study was to develop random and aligned polyacrilonitrile (PAN)/polypyrrole (PPy) nanofibrous scaffolds by electrospinning technique for osteogenic differentiation of mesenchymal stem cells. Nanofibers were ...

• Characterization of long living yeast deletion mutants that lack mitochondrial metabolism genes DSS1, PPA2 and AFG3 

  Muid, K. A.; Kimyon, Onder; Reza, Shahadat Hasan; Karakaya, Huseyin Caglar; Koc, Ahmet (Elsevier, 2019)

  Molecular mechanisms of aging and longevity are still mostly unknown. Mitochondria play central roles in cellular metabolism and aging. In this study, we identified three deletion mutants of mitochondrial metabolism genes ...

• Chitosan/montmorillonite composite nanospheres for sustained antibiotic delivery at post-implantation bone infection treatment 

  Kimna, Ceren; Deger, Sibel; Tamburaci, Sedef; Tihminlioglu, Funda (Iop Publishing Ltd, 2019)

  Despite the advancements in bone transplantation operations, inflammation is still a serious problem that threatens human health at the post-implantation period. Conventional antibiotic therapy methods may lead to some ...

• Novel zein-based multilayer wound dressing membranes with controlled release of gentamicin 

  Kimna, Ceren; Tamburaci, Sedef; Tihminlioglu, Funda (Wiley, 2019)

  Recently, functional multilayer scaffolds with controlled drug release ability come into prominence for wound healing applications to mimic the layered structure of skin tissue and prevent the possible infections at the ...

• Use of FTIR and UV-visible spectroscopy in determination of chemical characteristics of olive oils 

  Uncu, Oguz; Ozen, Banu; Tokatli, Figen (Elsevier, 2019)

  It was aimed to predict fatty acid ethyl ester (FAEE), wax, diacylglycerol (DAG) and color pigment contents of olive oils by using rapid and non-destructive spectroscopic techniques (FTIR and UV-vis) individually and in ...

• Fiber Bragg grating regeneration at 450 degrees C for improved high temperature sensing 

  Chah, Karima; Yuksel, Kivilcim; Kinet, Damien; Yazd, Nazila Safari; Megret, Patrice; Caucheteur, Christophe (Optical Soc Amer, 2019)

  Type-I fiber Bragg gratings photo-inscribed in hydrogen-loaded B/Ge co-doped silica single-mode optical fibers have been regenerated efficiently at 450 degrees C, which is the lowest temperature reported so far. The ...

• Defect tolerant and dimension dependent ferromagnetism in MnSe2 

  Eren, I.; Iyikanat, F.; Sahin, H. (Royal Soc Chemistry, 2019)

  By performing density functional theory-based calculations, we investigate the structural, vibrational, electronic and magnetic properties of 2D monolayers, nanoribbons and quantum dots of MnSe2. Vibrational spectrum ...

• Flow-through colorimetric assay for detection of nucleic acids in plasma 

  Ammanath, Gopal; Yeasmi, Sanjida; Srinivasulu, Yuvasri; Vats, Mukti; Cheema, Jamal Ahmed; Nabilah, Fairuz; Liedberg, Bo (Elsevier Science Bv, 2019)

  A flow-through colorimetric assay for detection of nucleic acids in plasma is reported. The proposed assay features an array of four polyvinylidene fluoride (PVDF) membranes impregnated with cationic poly (3-alkoxy-4-met ...

• Single Chain Cationic Polymer Dot as a Fluorescent Probe for Cell Imaging and Selective Determination of Hepatocellular Carcinoma Cells 

  Ozenler, Sezer; Yucel, Muge; Tuncel, Ozge; Kaya, Hakan; Ozcelik, Serdar; Yildiz, Umit Hakan (Amer Chemical Soc, 2019)

  This letter describes formation of single chain cationic polymer dots (Pdots) made of poly[1,4-dimethy1-1-(34(2,4,5-trimethylthiophen-3-yl)oxy)propyl)piperazin-1-ium bromide] conjugated polyelectrolyte (CPE). The single ...

• Development of a High-Flux Thin-Film Composite Nanofiltration Membrane with Sub-Nanometer Selectivity Using a pH and Temperature-Responsive Pentablock Co-Polymer 

  Bar, Canbike; Caglar, Nagahan; Uz, Metin; Mallapragada, Surya K.; Altinkaya, Sacide Alsoy (Amer Chemical Soc, 2019)

  Producing block co-polymer-based nanofiltration (NF) membranes with sharp molecular weight cutoffs via an efficient method exhibiting persistent size-based separation quality is challenging. In this study, this challenge ...

• A portable microfluidic platform for rapid determination of microbial load and somatic cell count in milk 

  Duven, Gamze; Cetin, Barbaros; Kurtuldu, Huseyin; Gunduz, Guelten Tiryaki; Tavman, Sebnem; Kisla, Duygu (Springer, 2019)

  Microfluidics systems that have been emerged in the last 20years and used for processing the fluid in a microchannel structure at microliter levels are alternative to the conventional methods. The objective of the study ...

• Genomewide Elucidation of Drug Resistance Mechanisms for Systemically Used Antifungal Drugs Amphotericin B, Caspofungin, and Voriconazole in the Budding Yeast 

  Balkan, Cigdem; Ercan, Ilkcan; Isik, Esin; Akdeniz, Esra Sahin; Balcioglu, Orhan; Kodedova, Marie; Koc, Ahmet (Amer Soc Microbiology, 2019)

  There are only a few antifungal drugs used systemically in treatment, and invasive fungal infections that are resistant to these drugs are an emerging problem in health care. In this study, we performed a high-copy-number ...

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