Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/9514
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dc.contributor.authorAkgül, Bünyamin-
dc.contributor.authorErdoğan, İpek-
dc.date.accessioned2020-07-25T22:12:45Z-
dc.date.available2020-07-25T22:12:45Z-
dc.date.issued2018-
dc.identifier.issn1664-8021-
dc.identifier.urihttps://doi.org/10.3389/fgene.2018.00403-
dc.identifier.urihttps://hdl.handle.net/11147/9514-
dc.descriptionPubMed: 30298086en_US
dc.description.abstractMicroRNAs (miRNAs) are a conserved class of non-coding RNAs of 22 nucleotides that post-transcriptionally regulate gene expression through translational repression and/or mRNA degradation. A great progress has been made regarding miRNA biogenesis and miRNA-mediated gene regulation. Additionally, an ample amount of information exists with respect to the regulation of miRNAs. However, the cytoplasmic localization of miRNAs and its effect on gene regulatory output is still in progress. We provide a current review of the cytoplasmic miRNA localization in metazoans. We then discuss the dynamic changes in the intracytoplasmic localization of miRNAs as a means to regulate their silencing activity. We then conclude our discussion with the potential molecules that could modulate miRNA localization.en_US
dc.language.isoenen_US
dc.publisherFrontiers Media S.A.en_US
dc.relation.ispartofFrontiers in Geneticsen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMicroRNAsen_US
dc.subjectLocalizationen_US
dc.subjectPolysomeen_US
dc.subjectmRNPen_US
dc.subjectTranslational repressionen_US
dc.titleIntracytoplasmic re-localization of miRISC complexesen_US
dc.typeArticleen_US
dc.authorid0000-0001-6415-7654-
dc.authorid0000-0001-9877-9689-
dc.institutionauthorAkgül, Bünyamin-
dc.institutionauthorErdoğan, İpek-
dc.departmentIzmir Institute of Technology. Molecular Biology and Geneticsen_US
dc.identifier.volume9en_US
dc.identifier.wosWOS:000445124200001en_US
dc.identifier.scopus2-s2.0-85055214296en_US
dc.relation.publicationcategoryDiğeren_US
dc.identifier.doi10.3389/fgene.2018.00403-
dc.identifier.pmid30298086en_US
dc.relation.doi10.3389/fgene.2018.00403en_US
dc.coverage.doi10.3389/fgene.2018.00403en_US
dc.identifier.scopusqualityQ2-
item.openairetypeArticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextWith Fulltext-
item.cerifentitytypePublications-
item.languageiso639-1en-
item.grantfulltextopen-
crisitem.author.dept04.03. Department of Molecular Biology and Genetics-
Appears in Collections:Molecular Biology and Genetics / Moleküler Biyoloji ve Genetik
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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