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https://hdl.handle.net/11147/9125
Title: | IL-17, IL-21, and IL-22 Cytokines of T Helper 17 Cells in Cancer | Authors: | Nalbant, Ayten | Keywords: | Th17 cells IL-17 cancer IL-21 IL-22 |
Issue Date: | 2019 | Publisher: | Mary Ann Liebert Inc. | Abstract: | CD4(+) T helper (Th) cells are important regulators of cellular immune response. Newly discovered interleukin (IL)-17-producing CD4(+) T cells are known as T helper 17 cells (Th17). They are distinct subset from the T helper type 1 (Th1) and 2 (Th2) lineages. The differentiation of Th17 cells has been intensively studied; however, the role of Th17 cells in different diseases including cancer is still under investigation. Besides IL-17 family cytokines, Th17 cells produce IL-22, IL-21, and IL-26. The dysregulated function of Th17 cells and their cytokines could contribute to pathology of diseases, including cancer. The role of cytokines of Th17 cells such as IL-17, IL-21, and IL-22 in cancer will be discussed in this review. | Description: | WOS: 000463009500006 PubMed: 30562123 |
URI: | https://doi.org/10.1089/jir.2018.0057 https://hdl.handle.net/11147/9125 |
ISSN: | 1079-9907 1557-7465 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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