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dc.contributor.authorAvcı, Çığır Biray
dc.contributor.authorBaran, Yusuf
dc.date.accessioned2020-02-12T13:10:36Z
dc.date.available2020-02-12T13:10:36Z
dc.date.issued2014en_US
dc.identifier.citationAvcı, Ç. B., and Baran, Y. (2014). Use of microRNAs in personalized medicine. Methods in Molecular Biology, 1107, 311-325. doi:10.1007/978-1-62703-748-8_19en_US
dc.identifier.issn1064-3745
dc.identifier.urihttps://doi.org/10.1007/978-1-62703-748-8_19
dc.identifier.urihttps://hdl.handle.net/11147/7693
dc.description.abstractPersonalized medicine comprises the genetic information together with the phenotypic and environmental factors to yield healthcare tailored to an individual and removes the limitations of the "one-size-fits-all" therapy approach. This provides the opportunity to translate therapies from bench to clinic, to diagnose and predict disease, and to improve patient-tailored treatments based on the unique signatures of a patient's disease and further to identify novel treatment schedules. Nowadays, tiny noncoding RNAs, called microRNAs, have captured the spotlight in molecular biology with highlights like their involvement in DNA translational control, their impression on mRNA and protein expression levels, and their ability to reprogram molecular signaling pathways in cancer. Realizing their pivotal roles in drug resistance, they emerged as diagnostic targets orchestrating drug response in individualized therapy examples. It is not premature to think that researchers could have the US Food and Drug Administration (FDA)-approved kit-based assays for miRNA analysis in the near future. We think that miRNAs are ready for prime time.en_US
dc.language.isoengen_US
dc.publisherSpringeren_US
dc.relation.isversionof10.1007/978-1-62703-748-8_19en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectmiRNAsen_US
dc.subjectPersonalized medicineen_US
dc.subjectPharmacogenomicsen_US
dc.subjectMessenger RNAen_US
dc.titleUse of microRNAs in personalized medicineen_US
dc.typearticleen_US
dc.contributor.authorID0000-0002-1056-4673en_US
dc.contributor.institutionauthorBaran, Yusuf
dc.relation.journalMethods in Molecular Biologyen_US
dc.contributor.departmentIzmir Institute of Technology. Molecular Biology and Geneticsen_US
dc.identifier.volume1107en_US
dc.identifier.startpage311en_US
dc.identifier.endpage325en_US
dc.identifier.wosWOS:000329167800020
dc.identifier.scopusSCOPUS:2-s2.0-84891759974
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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