Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/7136
Title: NMR studies on natural and synthetic Amavadin
Authors: Armstrong, Elaine M.
Collison, David
Ertok, Nigar
Garner, Catherine D.
Ertok, Nigar
Izmir Institute of Technology. Chemistry
Keywords: Amavadin
Bioinorganic chemistry
Natural products
Vanadium(IV)
Issue Date: Oct-2000
Publisher: Elsevier Ltd.
Source: Armstrong, E. M., Collison, D., Ertok, N. and Garner, C. D. (2000). NMR studies on natural and synthetic Amavadin. Talanta, 53(1), 75-87. doi:10.1016/S0039-9140(00)00376-3
Abstract: The stereochemistry of isolated natural product Amavadin, which contains a 1:2 complex of V(IV) with N-hydroxyimino-2,2′-dipropionic acid (HIDPAH3), and some synthetic complexes have been investigated. Amavadin was isolated from Amanita muscaria and oxidized with [NH4]2[Ce(NO3)6]. H2[Δ-V(S,S-HIDPA)2].3H2O, H2[Δ,Λ-V(S,S-HIDPA)2].3H2O and their equivalent oxidized species have been synthesized and characterized spectroscopically. A combination of COSY, NOE, 1H, 13C-NMR and CD spectroscopy have been used to prove that the isolated natural product Amavadin consists of an almost equal mixture of the Δ- and Λ-isomers of [V(S,S-HIDPA)2]2-. The stereochemistry of isolated natural product Amavadin, which contains a 1:2 complex of V(IV) with N-hydroxyimino-2,2'-dipropionic acid (HIDPAH3), and some synthetic complexes have been investigated. Amavadin was isolated from Amanita muscaria and oxidized with [NH4]2[Ce(NO3)6]. H2[Δ-V(S,S-HIDPA)2].3H2O, H2[Δ,Λ-V(S,S-HIDPA)2].3H2O and their equivalent oxidized species have been synthesized and characterized spectroscopically. A combination of COSY, NOE, 1H, 13C-NMR and CD spectroscopy have been used to prove that the isolated natural product Amavadin consists of an almost equal mixture of the Δ- and Λ-isomers of [V(S,S-HIDPA)2]2-.
URI: https://doi.org/10.1016/S0039-9140(00)00376-3
http://hdl.handle.net/11147/7136
ISSN: 0039-9140
1873-3573
Appears in Collections:Chemistry / Kimya
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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