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Title: T cells in tumor microenvironment
Authors: Kiraz, Yağmur
Baran, Yusuf
Nalbant, Ayten
Kiraz, Yağmur
Baran, Yusuf
Nalbant, Ayten
Izmir Institute of Technology. Molecular Biology and Genetics
Keywords: Cancer immunology
T cells
T helper cells
Tumor microenvironment
Th17 cells
Issue Date: Jan-2016
Publisher: SAGE Publications Inc.
Source: Kiraz, Y., Baran, Y., and Nalbant, A. (2016). T cells in tumor microenvironment. Tumor Biology, 37(1), 39-45. doi:10.1007/s13277-015-4241-1
Abstract: Tumors progress in a specific area, which supports its development, spreading or shrinking in time with the presence of different factors that effect the fate of the cancer cells. This specialized site is called “tumor microenvironment” and has a composition of heterogenous materials. The immune cells are also residents of this stromal, cancerous, and inflammatory environment, and their types, densities, or functional differences are one of the key factors that mediate the fate of a tumor. T cells as a vital part of the immune system also are a component of tumor microenvironment, and their roles have been elucidated in many studies. In this review, we focused on the immune system components by focusing on T cells and detailed T helper cell subsets in tumor microenvironment and how their behaviors affect either the tumor or the patient’s outcome. © 2015, International Society of Oncology and BioMarkers (ISOBM).
ISSN: 1423-0380
Appears in Collections:Molecular Biology and Genetics / Moleküler Biyoloji ve Genetik
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Sürdürülebilir Yeşil Kampüs Koleksiyonu / Sustainable Green Campus Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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