Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/4796
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dc.contributor.authorAbaan, Ogan Demir-
dc.contributor.authorMutlu, Pelin Kaya-
dc.contributor.authorBaran, Yusuf-
dc.contributor.authorAtalay, Can-
dc.contributor.authorGündüz, Ufuk-
dc.date.accessioned2017-02-07T07:31:40Z
dc.date.available2017-02-07T07:31:40Z
dc.date.issued2009-02
dc.identifier.citationAbaan, O. D., Mutlu, P. K., Baran, Y., Atalay, C. and Gündüz, U. (2009). Multidrug resistance mediated by MRP1 gene overexpression in breast cancer patients. Cancer Investigation, 27(2), 201-205. doi:10.1080/07357900802173562en_US
dc.identifier.issn0735-7907
dc.identifier.issn0735-7907-
dc.identifier.urihttp://dx.doi.org/10.1080/07357900802173562
dc.identifier.urihttp://hdl.handle.net/11147/4796
dc.description.abstractMultidrug resistance (MDR) is a serious handicap towards the effective treatment of breast cancer patients. One of the most prevalent MDR mechanisms is through the overexpression of genes coding the proteins called Multidrug Resistance-associated Proteins (MRPs). The aim of this study was to investigate the expression of MRP1 in tumor tissues from breast cancer patients. In this study, a semi-quantitative RT-PCR approach was utilized. Our results suggest that MRP1 overexpression can mediate MDR in patients. Pre-evaluation of the level of such MDR mediators before chemotherapy can increase the efficacy of the treatment.en_US
dc.language.isoenen_US
dc.publisherTaylor and Francis Ltd.en_US
dc.relation.ispartofCancer Investigationen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBreast canceren_US
dc.subjectChemotherapyen_US
dc.subjectMDRen_US
dc.subjectMRP Familyen_US
dc.subjectMRP1en_US
dc.titleMultidrug resistance mediated by MRP1 gene overexpression in breast cancer patientsen_US
dc.typeArticleen_US
dc.authoridTR119193en_US
dc.institutionauthorBaran, Yusuf-
dc.departmentİzmir Institute of Technology. Molecular Biology and Geneticsen_US
dc.identifier.volume27en_US
dc.identifier.issue2en_US
dc.identifier.startpage201en_US
dc.identifier.endpage205en_US
dc.identifier.wosWOS:000263649300011en_US
dc.identifier.scopus2-s2.0-60849098201en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1080/07357900802173562-
dc.identifier.pmid19235593en_US
dc.relation.doi10.1080/07357900802173562en_US
dc.coverage.doi10.1080/07357900802173562en_US
dc.identifier.wosqualityQ4-
dc.identifier.scopusqualityQ3-
item.fulltextWith Fulltext-
item.grantfulltextopen-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.openairetypeArticle-
crisitem.author.dept04.03. Department of Molecular Biology and Genetics-
Appears in Collections:Molecular Biology and Genetics / Moleküler Biyoloji ve Genetik
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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