Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/4624
Title: Tensile adhesion of type I collagen to titanium alloy and calcium phosphate coated surfaces with different roughness values
Authors: Özerdem, Barış
Keywords: Adhesion
Calcium phosphate
Surface roughness
Tensile strength
Titanium alloy
Publisher: IOS Press
Source: Özerdem, B. (2002). Tensile adhesion of type I collagen to titanium alloy and calcium phosphate coated surfaces with different roughness values. Bio-Medical Materials and Engineering, 12(4), 347-352.
Abstract: The purpose of total joint arthroplasty is to reduce pain and restore function. Its success depends on the formation of a new bone that stabilizes the prosthesis. The proposed solution for this important problem is to have bio-coated implant surfaces which are more conductive to bone growth. Additionally, collagen has long been used as a matrix for medical applications, because of its biocompatibility and adaptability. In this study, a test method for measuring the tensile adhesion strength of collagen to titanium alloy and calcium phosphate coated surfaces with different roughness values was developed, in order to evaluate how well the collagen adheres to the metallic and bio-coated surfaces. A precision motion system was used to stretch gels that were adherent to the plate surfaces. The tests were done in DMEM solution. The adhesive strength between the collagen gel and plate was significantly higher for calcium phosphate coated surfaces. Adhesive strength was highest in the sample with the highest roughness value.
URI: http://hdl.handle.net/11147/4624
ISSN: 0959-2989
0959-2989
Appears in Collections:Mechanical Engineering / Makina Mühendisliği
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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