Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/2717
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dc.contributor.authorAltıok, Duygu-
dc.contributor.authorAltıok, Evren-
dc.contributor.authorTıhmınlıoğlu, Funda-
dc.date.accessioned2017-01-04T12:52:13Z-
dc.date.available2017-01-04T12:52:13Z-
dc.date.issued2010-07-
dc.identifier.citationAltıok, D., Altıok, E., and Tıhmınlıoğlu, F. (2010). Physical, antibacterial and antioxidant properties of chitosan films incorporated with thyme oil for potential wound healing applications. Journal of Materials Science: Materials in Medicine, 21(7). 2227-2236. doi:10.1007/s10856-010-4065-xen_US
dc.identifier.isbn0957-4530-
dc.identifier.issn0957-4530-
dc.identifier.urihttp://doi.org/10.1007/s10856-010-4065-x-
dc.identifier.urihttp://hdl.handle.net/11147/2717-
dc.description.abstractChitosan films incorporated with thyme oil for potential applications of wound dressing were successfully prepared by solvent casting method. The water vapor permeability, oxygen transmission rate, and mechanical properties of the films were determined. Surface and cross-section morphologies and the film thicknesses were determined by Scanning Electron Microscopy (SEM). Fourier transform infrared (FT-IR) spectroscopy was conducted to determine functional group interactions between the chitosan and thyme oil. Thermal behaviors of the films were analyzed by Thermal Gravimetry (TGA) and Differential Scanning Calorimetry (DSC). In addition, the antimicrobial and the antioxidant activities of the films were investigated. The antimicrobial test was carried by agar diffusion method and the growth inhibition effects of the films including different amount of thyme oil were tested on the gram negative microorganisms of Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and a gram positive microorganism of Staphylococcus aureus. The minimum thyme oil concentration in chitosan films showing the antimicrobial activity on all microorganisms used in the study was found as 1.2 % (v/v). In addition, this concentration showed the highest antioxidant activity due to mainly the carvacrol in thyme oil. Water vapor permeability and oxygen transmission rate of the films slightly increased, however, mechanical properties decreased with thyme oil incorporation. The results revealed that the thyme oil has a good potential to be incorporated into chitosan to make antibacterial and permeable films for wound healing applications. © 2010 Springer Science+Business Media, LLC.en_US
dc.language.isoenen_US
dc.publisherSpringer Verlagen_US
dc.relation.ispartofJournal of Materials Science: Materials in Medicineen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMechanical permeabilityen_US
dc.subjectAntioxidant activitiesen_US
dc.subjectChitosan filmen_US
dc.subjectOxygen permeable membranesen_US
dc.subjectWound dressingsen_US
dc.titlePhysical, antibacterial and antioxidant properties of chitosan films incorporated with thyme oil for potential wound healing applicationsen_US
dc.typeArticleen_US
dc.authoridTR1143en_US
dc.institutionauthorAltıok, Duygu-
dc.institutionauthorAltıok, Evren-
dc.institutionauthorTıhmınlıoğlu, Funda-
dc.departmentİzmir Institute of Technology. Chemical Engineeringen_US
dc.identifier.volume21en_US
dc.identifier.issue7en_US
dc.identifier.startpage2227en_US
dc.identifier.endpage2236en_US
dc.identifier.wosWOS:000279592600023en_US
dc.identifier.scopus2-s2.0-77954540911en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1007/s10856-010-4065-x-
dc.identifier.pmid20372985en_US
dc.relation.doi10.1007/s10856-010-4065-xen_US
dc.coverage.doi10.1007/s10856-010-4065-xen_US
dc.identifier.wosqualityQ2-
dc.identifier.scopusqualityQ1-
dc.identifier.wosqualityttpTop10%en_US
item.languageiso639-1en-
item.cerifentitytypePublications-
item.grantfulltextopen-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypeArticle-
item.fulltextWith Fulltext-
crisitem.author.dept03.02. Department of Chemical Engineering-
Appears in Collections:Chemical Engineering / Kimya Mühendisliği
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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