Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/2333
Title: The effects of urease immobilization on the transport characteristics and protein adsorption capacity of cellulose acetate based hemodialysis membranes
Authors: Yaşar Mahlıçlı, Filiz
Altınkaya, Sacide
Yaşar Mahlıçlı, Filiz
Altınkaya, Sacide
Izmir Institute of Technology. Chemical Engineering
Keywords: Permeation
Alternative methods
Cellulose acetates
Uric acids
Hemodialysis membranes
Transport characteristics
Issue Date: Oct-2009
Publisher: Springer Verlag
Source: Yaşar Mahlıçlı, F., and Alsoy Altınkaya, S. (2009). The effects of urease immobilization on the transport characteristics and protein adsorption capacity of cellulose acetate based hemodialysis membranes. Journal of Materials Science: Materials in Medicine, 20(10), 2167-2179. doi:10.1007/s10856-009-3776-3
Abstract: In this study, cellulose acetate (CA) based hemodialysis membranes were prepared by a dry phase inversion method and the influences of urease immobilization on the clearing performance and protein adsorption capacity of the membranes were investigated. Permeation experiments have shown that modification of CA membranes with urease immobilization not only enhanced the transport rate of urea but also increased the permeation coefficients of uric acid and creatinine by changing the structure of the membrane. Furthermore, the protein adsorption capacity of the CA membranes decreased. On the other hand, the mechanical strength of the modified CA membrane did not change significantly compared with that of the unmodified one. A mathematical model was derived to determine the rate of mass transfer of urea through modified CA membranes. Model predictions along with the experimental data suggest that urease immobilization can be used as an alternative method in preparing CA based hemodialysis membranes with improved transport characteristics and biocompatibility through reduced protein adsorption capacities.
URI: http://dx.doi.org/10.1007/s10856-009-3776-3
http://hdl.handle.net/11147/2333
ISSN: 0957-4530
0957-4530
Appears in Collections:Chemical Engineering / Kimya Mühendisliği
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

Files in This Item:
File Description SizeFormat 
2333.pdfMakale606.3 kBAdobe PDFThumbnail
View/Open
Show full item record

CORE Recommender

SCOPUSTM   
Citations

4
checked on Jun 12, 2021

WEB OF SCIENCETM
Citations

5
checked on Jun 12, 2021

Google ScholarTM

Check

Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.