Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/2273
Title: Complex coacervation of silk fibroin and hyaluronic acid
Authors: Malay, Özge
Bayraktar, Oğuz
Batıgün, Ayşegül
Keywords: Complex coacervation
Hyaluronic acid
Protein-polysaccharide interactions
Silk fibroin
Issue Date: Mar-2007
Publisher: Elsevier Ltd.
Source: Malay, Ö., Bayraktar, O., and Batıgün, A. (2007). Complex coacervation of silk fibroin and hyaluronic acid. International Journal of Biological Macromolecules, 40(4), 387-393. doi:10.1016/j.ijbiomac.2006.09.017
Abstract: This study aimed to investigate the pH-induced complexation of silk fibroin (SF) and hyaluronic acid (HA). SF-HA complex coacervation was investigated by monitoring turbidity of the SF-HA system under slow acidification. Gravimetric analysis was performed to determine the yield of complex coacervation and viscosity of the system was measured to study the formation of the complexes at different pH values. The influences of total biopolymer concentration and biopolymer weight ratio on complex coacervation were examined during the analyses. Formation of the complexes was evidenced by the minimum viscosity and the maximum turbidity observed in the system. SF-HA complexes were formed within the pH-window of 2.5-3.5 regardless of the total biopolymer concentration or biopolymer ratio. Complex coacervation of SF-HA showed a reversible behavior and coacervation could be handled even in excess amounts of the biopolymers, which pointed out a non-stoichiometric complexation.
URI: http://doi.org/10.1016/j.ijbiomac.2006.09.017
http://hdl.handle.net/11147/2273
ISSN: 0141-8130
0141-8130
1879-0003
Appears in Collections:Chemical Engineering / Kimya Mühendisliği
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

Files in This Item:
File Description SizeFormat 
2273.pdfMakale441.18 kBAdobe PDFThumbnail
View/Open
Show full item record

CORE Recommender

SCOPUSTM   
Citations

52
checked on Dec 4, 2021

WEB OF SCIENCETM
Citations

54
checked on Dec 4, 2021

Page view(s)

24
checked on Dec 4, 2021

Download(s)

58
checked on Dec 4, 2021

Google ScholarTM

Check

Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.