Please use this identifier to cite or link to this item:
https://hdl.handle.net/11147/11474
Title: | Benzodiazepine derivatives from marine-derived Streptomyces cacaoi 14cm034 | Authors: | Çetinel Aksoy, Semiha Küçüksolak, Melis Uzel, Ataç Bedir, Erdal |
Keywords: | Marine actinobacterium Streptomyces cacaoi Benzodiazepine Antimicrobial activity Antibiotics |
Publisher: | ACG Publications | Abstract: | 7-methoxy-8-hydroxy cycloanthranilylproline (2), a new natural product with pyrrolobenzodiazepine (PBD) framework, was isolated from marine-derived actinobacterium Streptomyces cacaoi 14CM034, together with cycloanthranilylproline (1). Structural elucidation of the compounds was based on FTIR, 1D-(H-1 and C-13 NMR), 2D-NMR (COSY, HMBC and NOESY) and HR-MS analyses. Compounds 1 and 2 exhibited notable antimicrobial activity. The presence of PBD derivatives in S. cacaoi was first demonstrated with this study. | URI: | https://doi.org/10.25135/rnp.203.20.08.1766 https://hdl.handle.net/11147/11474 |
ISSN: | 1307-6167 |
Appears in Collections: | Bioengineering / Biyomühendislik Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection TR Dizin İndeksli Yayınlar / TR Dizin Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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20210528184848A14-203-RNP-2008-1766.pdf | 549.53 kB | Adobe PDF | View/Open |
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