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https://hdl.handle.net/11147/11474
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Çetinel Aksoy, Semiha | - |
dc.contributor.author | Küçüksolak, Melis | - |
dc.contributor.author | Uzel, Ataç | - |
dc.contributor.author | Bedir, Erdal | - |
dc.date.accessioned | 2021-11-06T09:49:34Z | - |
dc.date.available | 2021-11-06T09:49:34Z | - |
dc.date.issued | 2021 | - |
dc.identifier.issn | 1307-6167 | - |
dc.identifier.uri | https://doi.org/10.25135/rnp.203.20.08.1766 | - |
dc.identifier.uri | https://hdl.handle.net/11147/11474 | - |
dc.description.abstract | 7-methoxy-8-hydroxy cycloanthranilylproline (2), a new natural product with pyrrolobenzodiazepine (PBD) framework, was isolated from marine-derived actinobacterium Streptomyces cacaoi 14CM034, together with cycloanthranilylproline (1). Structural elucidation of the compounds was based on FTIR, 1D-(H-1 and C-13 NMR), 2D-NMR (COSY, HMBC and NOESY) and HR-MS analyses. Compounds 1 and 2 exhibited notable antimicrobial activity. The presence of PBD derivatives in S. cacaoi was first demonstrated with this study. | en_US |
dc.description.sponsorship | This work was supported by the Scientific and Technological Research Council of Turkey (TUBITAK, Project No: 109S361) and EBILTEM (2012/BIL/028). | en_US |
dc.language.iso | en | en_US |
dc.publisher | ACG Publications | en_US |
dc.relation.ispartof | Records of Natural Products | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Marine actinobacterium | en_US |
dc.subject | Streptomyces cacaoi | en_US |
dc.subject | Benzodiazepine | en_US |
dc.subject | Antimicrobial activity | en_US |
dc.subject | Antibiotics | en_US |
dc.title | Benzodiazepine derivatives from marine-derived Streptomyces cacaoi 14cm034 | en_US |
dc.type | Article | en_US |
dc.authorid | 0000-0003-1262-063X | - |
dc.institutionauthor | Küçüksolak, Melis | - |
dc.institutionauthor | Bedir, Erdal | - |
dc.department | İzmir Institute of Technology. Bioengineering | en_US |
dc.identifier.volume | 15 | en_US |
dc.identifier.issue | 6 | en_US |
dc.identifier.startpage | 602 | en_US |
dc.identifier.endpage | 607 | en_US |
dc.identifier.wos | WOS:000658306500015 | en_US |
dc.identifier.scopus | 2-s2.0-85108653316 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.25135/rnp.203.20.08.1766 | - |
local.message.claim | 2022-06-08T12:08:02.861+0300 | * |
local.message.claim | |rp02870 | * |
local.message.claim | |submit_approve | * |
local.message.claim | |dc_contributor_author | * |
local.message.claim | |None | * |
dc.identifier.trdizinid | 464301 | en_US |
dc.identifier.wosquality | Q3 | - |
dc.identifier.scopusquality | Q3 | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
item.fulltext | With Fulltext | - |
item.openairetype | Article | - |
item.languageiso639-1 | en | - |
crisitem.author.dept | 03.01. Department of Bioengineering | - |
crisitem.author.dept | 03.01. Department of Bioengineering | - |
Appears in Collections: | Bioengineering / Biyomühendislik Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection TR Dizin İndeksli Yayınlar / TR Dizin Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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File | Size | Format | |
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20210528184848A14-203-RNP-2008-1766.pdf | 549.53 kB | Adobe PDF | View/Open |
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