Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/11474
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dc.contributor.authorÇetinel Aksoy, Semiha-
dc.contributor.authorKüçüksolak, Melis-
dc.contributor.authorUzel, Ataç-
dc.contributor.authorBedir, Erdal-
dc.date.accessioned2021-11-06T09:49:34Z-
dc.date.available2021-11-06T09:49:34Z-
dc.date.issued2021-
dc.identifier.issn1307-6167-
dc.identifier.urihttps://doi.org/10.25135/rnp.203.20.08.1766-
dc.identifier.urihttps://hdl.handle.net/11147/11474-
dc.description.abstract7-methoxy-8-hydroxy cycloanthranilylproline (2), a new natural product with pyrrolobenzodiazepine (PBD) framework, was isolated from marine-derived actinobacterium Streptomyces cacaoi 14CM034, together with cycloanthranilylproline (1). Structural elucidation of the compounds was based on FTIR, 1D-(H-1 and C-13 NMR), 2D-NMR (COSY, HMBC and NOESY) and HR-MS analyses. Compounds 1 and 2 exhibited notable antimicrobial activity. The presence of PBD derivatives in S. cacaoi was first demonstrated with this study.en_US
dc.description.sponsorshipThis work was supported by the Scientific and Technological Research Council of Turkey (TUBITAK, Project No: 109S361) and EBILTEM (2012/BIL/028).en_US
dc.language.isoenen_US
dc.publisherACG Publicationsen_US
dc.relation.ispartofRecords of Natural Productsen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMarine actinobacteriumen_US
dc.subjectStreptomyces cacaoien_US
dc.subjectBenzodiazepineen_US
dc.subjectAntimicrobial activityen_US
dc.subjectAntibioticsen_US
dc.titleBenzodiazepine derivatives from marine-derived Streptomyces cacaoi 14cm034en_US
dc.typeArticleen_US
dc.authorid0000-0003-1262-063X-
dc.institutionauthorKüçüksolak, Melis-
dc.institutionauthorBedir, Erdal-
dc.departmentIzmir Institute of Technology. Bioengineeringen_US
dc.identifier.volume15en_US
dc.identifier.issue6en_US
dc.identifier.startpage602en_US
dc.identifier.endpage607en_US
dc.identifier.wosWOS:000658306500015en_US
dc.identifier.scopus2-s2.0-85108653316en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.25135/rnp.203.20.08.1766-
local.message.claim2022-06-08T12:08:02.861+0300|||rp02870|||submit_approve|||dc_contributor_author|||None*
item.languageiso639-1en-
item.openairetypeArticle-
item.cerifentitytypePublications-
item.grantfulltextopen-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextWith Fulltext-
crisitem.author.dept03.01. Department of Bioengineering-
crisitem.author.dept03.01. Department of Bioengineering-
Appears in Collections:Bioengineering / Biyomühendislik
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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