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https://hdl.handle.net/11147/10233
Title: | 1,2-Diborolanes with strong donor substituents: Synthesis and high antimicrobial activity | Authors: | Şahin, Yüksel Poyrazoğlu Çoban, Esin Sevinçek, Resul Bıyık, Halil H. Özgener, Hüseyin Aygün, Muhittin |
Keywords: | Antimicrobial Diboracyclopentane Diborolane Heterocycles |
Issue Date: | 2020 | Publisher: | Academic Press Inc. | Abstract: | 1,2-diborolanes with strong and without strong donor substituents have been described, and are also referred to as 1,2-diboracyclopentane. The 1,2-diaryl/alkyl-amino-1,2-diboracyclopentanes 2, 3, and 4 were obtained in good yield after the reaction of 1,2-dichloro-1,2-diboracyclopentane 1 with ArNHLi and Me3Si-NR2. The structures of these new derivatives were characterized by nuclear magnetic resonance spectroscopy. The molecular structures of 2b, 2c, 2e, 4, and 5f were also determined by single-crystal X-ray diffraction. The newly synthesized 1,2-borolanes are stable in air and showed particularly high activity against some Gram-positive bacteria. © 2020 Elsevier Inc. | URI: | https://doi.org/10.1016/j.bioorg.2020.104494 https://hdl.handle.net/10233 |
ISSN: | 0045-2068 1090-2120 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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