Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/9518
Title: Application of low intensity mechanical vibrations for bone tissue maintenance and regeneration
Authors: Ölçüm, Melis
Baskan, Öznur
Karadaş, Özge
Özçivici, Engin
Keywords: Vibrations
Osteoporosis
Osteogenesis
Cellular biomechanics
Osteoblasts
Mesenchymal stem cells
Issue Date: 2016
Publisher: TÜBİTAK
Abstract: Physical exercise is beneficial for bone tissue health, yet its usage is limited for preventing osteoporosis. Even though natural for the bone tissue from development to homeostasis, mechanical loads present with a multitude of physical parameters, including amplitude, duration, frequency, and distribution. Utilizing the most beneficial parameters of mechanical loads may potentiate a nonpharmaceutical tool for biotechnology to prevent and treat bone loss related to aging, bedrest, sedentary lifestyles, weightlessness, and other diseases. Low intensity vibrations (LIVs) consist of mechanical loads with amplitudes smaller than loads prescribed by habitual activity, with a higher frequency. In this review, literature covering LIV signal application on bone tissue and cellular and molecular level is presented. Studies indicate that LIV signals are safe, anabolic, and anticatabolic for skeletal tissue and are of great significance in regenerative medicine applications.
URI: https://doi.org/10.3906/biy-1506-76
https://hdl.handle.net/11147/9518
https://app.trdizin.gov.tr/makale/TWpFME5qUTFOUT09
ISSN: 1300-0152
1303-6092
Appears in Collections:Bioengineering / Biyomühendislik
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
TR Dizin İndeksli Yayınlar / TR Dizin Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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