Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/5410
Title: Invadopodia: Proteolytic feet of cancer cells
Authors: Batı, Gizem
Pesen Okvur, Devrim
Batı, Gizem
Pesen Okvur, Devrim
Izmir Institute of Technology. Molecular Biology and Genetics
Keywords: Cancer cells
Cortactin
Invadopodia
Metastasis
Issue Date: 2014
Publisher: TUBITAK
Source: Batı, G., and Pesen Okvur, D. (2014). Invadopodia: Proteolytic feet of cancer cells. Turkish Journal of Biology, 38(6), 740-747. doi:10.3906/biy-1404-110
Abstract: The leading cause of death in cancer patients is metastasis. Invasion is an integral part of metastasis and is carried out by proteolytic structures called invadopodia at the cellular level. In this introductory review, we start by evaluating the definition of invadopodia. While presenting the upstream signaling events involved, we integrate current models on invadopodia. In addition, we discuss the significance of invadopodia in 2D and 3D and in vivo. We finally point out technical challenges and conclude with open questions in the field. © TÜBİTAK.
URI: http://doi.org/10.3906/biy-1404-110
http://hdl.handle.net/11147/5410
ISSN: 1300-0152
1303-6092
Appears in Collections:Molecular Biology and Genetics / Moleküler Biyoloji ve Genetik
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
TR Dizin İndeksli Yayınlar / TR Dizin Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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