Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/13201
Title: Neo-Clerodanes From Teucrium Divaricatum Subsp. Divaricatum and Their Biological Activity Assessment
Authors: Aydoğan, Fadime
Ali, Zülfiqar
Zülfiqar, Fazila
Karaalp, Canan
Khan, Ikhlas A.
Bedir, Erdal
Keywords: Antimicrobial
iNOS
Lamiaceae
Publisher: Elsevier
Abstract: Fifteen neo-clerodane diterpenoids (1–15), including two undescribed glycosides, teudivaricosides A (1) and B (2), together with a known iridoid glycoside (16) and a phenylpropanoid glycoside (17) from the whole plant of Teucrium divaricatum subsp. divaricatum were isolated. Their structures were determined by spectral data analysis including 1D and 2D NMR and HRESIMS. Neo-clerodane diterpenoids were evaluated for their anti-inflammatory, and antimicrobial activities. None of them showed significant antimicrobial activity against various bacterial and fungal strains (up to 20 µg/mL). All tested compounds were inactive up to the highest tested concentration of 50 µM on iNOS inhibitory activity.
URI: https://doi.org/10.1016/j.phytol.2023.01.010
https://hdl.handle.net/11147/13201
ISSN: 1874-3900
Appears in Collections:Bioengineering / Biyomühendislik
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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