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Title: neo-Clerodanes from Teucrium divaricatum subsp. divaricatum and their biological activity assessment
Authors: Aydoğan, Fadime
Ali, Zülfiqar
Zülfiqar, Fazila
Karaalp, Canan
Khan, Ikhlas A.
Bedir, Erdal
Dicle Üniversitesi
University of Mississippi
University of Mississippi
Ege Üniversitesi
University of Mississippi
01. Izmir Institute of Technology
Keywords: Antimicrobial
Issue Date: Apr-2023
Publisher: Elsevier
Abstract: Fifteen neo-clerodane diterpenoids (1–15), including two undescribed glycosides, teudivaricosides A (1) and B (2), together with a known iridoid glycoside (16) and a phenylpropanoid glycoside (17) from the whole plant of Teucrium divaricatum subsp. divaricatum were isolated. Their structures were determined by spectral data analysis including 1D and 2D NMR and HRESIMS. Neo-clerodane diterpenoids were evaluated for their anti-inflammatory, and antimicrobial activities. None of them showed significant antimicrobial activity against various bacterial and fungal strains (up to 20 µg/mL). All tested compounds were inactive up to the highest tested concentration of 50 µM on iNOS inhibitory activity.
Appears in Collections:Bioengineering / Biyomühendislik
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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