Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/13201
Title: neo-Clerodanes from Teucrium divaricatum subsp. divaricatum and their biological activity assessment
Authors: Aydoğan, Fadime
Ali, Zülfiqar
Zülfiqar, Fazila
Karaalp, Canan
Khan, Ikhlas A.
Bedir, Erdal
Dicle Üniversitesi
University of Mississippi
University of Mississippi
Ege Üniversitesi
University of Mississippi
01. Izmir Institute of Technology
Keywords: Antimicrobial
iNOS
Lamiaceae
Issue Date: Apr-2023
Publisher: Elsevier
Abstract: Fifteen neo-clerodane diterpenoids (1–15), including two undescribed glycosides, teudivaricosides A (1) and B (2), together with a known iridoid glycoside (16) and a phenylpropanoid glycoside (17) from the whole plant of Teucrium divaricatum subsp. divaricatum were isolated. Their structures were determined by spectral data analysis including 1D and 2D NMR and HRESIMS. Neo-clerodane diterpenoids were evaluated for their anti-inflammatory, and antimicrobial activities. None of them showed significant antimicrobial activity against various bacterial and fungal strains (up to 20 µg/mL). All tested compounds were inactive up to the highest tested concentration of 50 µM on iNOS inhibitory activity.
URI: https://doi.org/10.1016/j.phytol.2023.01.010
https://hdl.handle.net/11147/13201
Appears in Collections:Bioengineering / Biyomühendislik
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection

Files in This Item:
File Description SizeFormat 
13201.pdf
  Until 2025-07-01
Article1 MBAdobe PDFView/Open    Request a copy
Show full item record




CORE Recommender

Page view(s)

52
checked on May 22, 2023

Google ScholarTM

Check




Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.