Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/12186
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dc.contributor.authorBaskan, Öznuren_US
dc.contributor.authorÖzçivici, Enginen_US
dc.date.accessioned2022-07-22T12:28:24Z-
dc.date.available2022-07-22T12:28:24Z-
dc.date.issued2022-03-
dc.identifier.urihttps://doi.org/10.1142/S0219519422500063-
dc.identifier.urihttps://hdl.handle.net/11147/12186-
dc.description.abstractMechanical forces are the integral determinants in cell and tissue homeostasis and regeneration, and they can affect numerous biological process from proliferation to fate determination. Mechanical forces that possess low magnitude and high frequency characteristics are also known as low intensity vibrations (LIVs). These signals were studied widely on many cell types for regenerative purposes, however most of these studies select components of LIV signals (e.g., magnitude, frequency, duration, etc.) arbitrarily. Here, we addressed the effect of LIV applied frequency, LIV daily exposure time and fate induction on the viability of preadipocyte 3T3-L1 cells. For this, we performed a frequency sweep that was ranging from 30Hz to 120Hz with 15Hz increments applied for 5, 10 or 20min during quiescent growth or adipogenesis for up to 10 days. Results suggest that the applied frequency and fate induction was an important determinant of cell viability while daily exposure time had no effect. These findings contribute to the effort of optimizing a relevant mechanical stimulus that can inhibit adipogenesis.en_US
dc.language.isoenen_US
dc.publisherWorld Scientific Publishingen_US
dc.relation.ispartofJournal of Mechanics in Medicine and Biologyen_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectAdipogenic differentiationen_US
dc.subjectBone marrow cellsen_US
dc.subjectPreadipocyteen_US
dc.subjectVibrationsen_US
dc.titleViability of 3T3-L1 preadipocytes is modulated by the applied frequency but not the exposure duration of low intensity vibratory stimulationen_US
dc.typeArticleen_US
dc.authorid0000-0003-2766-2381en_US
dc.authorid0000-0003-4464-0475en_US
dc.institutionauthorBaskan, Öznuren_US
dc.institutionauthorÖzçivici, Enginen_US
dc.departmentİzmir Institute of Technology. Bioengineeringen_US
dc.identifier.wosWOS:000765929400001en_US
dc.identifier.scopus2-s2.0-85126483676en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1142/S0219519422500063-
dc.contributor.affiliationIzmir Institute of Technologyen_US
dc.contributor.affiliationIzmir Institute of Technologyen_US
dc.relation.issn0219-5194en_US
dc.description.volume22en_US
dc.description.issue2en_US
dc.identifier.scopusqualityQ4-
item.openairetypeArticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextNo Fulltext-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.grantfulltextnone-
crisitem.author.dept01. Izmir Institute of Technology-
crisitem.author.dept03.01. Department of Bioengineering-
Appears in Collections:Bioengineering / Biyomühendislik
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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