Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/9866
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dc.contributor.authorKaraçalı, Bilge-
dc.date.accessioned2021-01-24T18:28:51Z-
dc.date.available2021-01-24T18:28:51Z-
dc.date.issued2012-
dc.identifier.isbn978-088986909-7-
dc.identifier.urihttps://doi.org/10.2316/P.2012.764-055-
dc.identifier.urihttps://hdl.handle.net/11147/9866-
dc.description.abstractWe present a new framework for global and local alignment of amino acid sequences based on hierarchical motif vectors that characterize local amino acid configurations. The motif vectors are constructed by carrying out wavelet decomposition on numeric property sequences obtained by replacing each amino acid in a sequence with their respective properties, and concatenating such profiles obtained for a large number of physico-chemical properties into a single column vector. We then formulate different schemes for aligning amino acid sequences based on their respective motif vectors globally as well as locally subject to measures of statistical significance. Experiment results indicate that the motif vectors accurately capture the amino acid composition at and around individual sites along sequences and allow associating sequence segments sharing similar functional attributes.en_US
dc.language.isoenen_US
dc.relation.ispartof9th IASTED International Conference on Biomedical Engineering, BioMed 2012en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAmino acid sequence analysisen_US
dc.subjectMotif vectorsen_US
dc.subjectPhysico-chemical profilesen_US
dc.subjectSequence alignmenten_US
dc.subjectWavelet decompositionen_US
dc.titleHierarchical motif vectors for amino acid sequence alignmenten_US
dc.typeConference Objecten_US
dc.institutionauthorKaraçalı, Bilge-
dc.departmentİzmir Institute of Technology. Electrical and Electronics Engineeringen_US
dc.identifier.startpage585en_US
dc.identifier.endpage592en_US
dc.identifier.scopus2-s2.0-84863688877en_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.2316/P.2012.764-055-
dc.relation.doi10.2316/P.2012.764-055en_US
dc.coverage.doi10.2316/P.2012.764-055en_US
item.openairetypeConference Object-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextNo Fulltext-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.grantfulltextnone-
crisitem.author.dept03.05. Department of Electrical and Electronics Engineering-
Appears in Collections:Electrical - Electronic Engineering / Elektrik - Elektronik Mühendisliği
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
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