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Title: Bioassay guided isolation of naphthoquinones from Onosma aksoyii, investigation of their cytotoxic properties
Authors: Kul, Demet
Karakoyun, Çiğdem
Yılmaz, Sinem
Pirhan, Ademi Fahri
Bedir, Erdal
Publisher: Georg Thieme Verlag
Abstract: The genus Onosma L. (Boraginaceae) includes about 230 species, distributed mainly in the Mediterranean region and Central Asia. Major constituents of Onosma species are alkaloids, naphthoquinones, polyphenols, phytosterols, terpenoids and fatty acids [1], [2]. Naphthoquinones are naturally widespread secondary metabolites deriving from some higher plants, fungi and bacteria. They exhibit significant biological activities such as cytotoxicity, antimalarial, antibacterial, antifungal and wound healing [2], [3]. Recently naphthoquinone derivatives have also been recognized as potent topoisomerase inhibitors [4].
Description: 67th International Congress and Annual Meeting of the Society-for-Medicinal-Plant-and-Natural-Product-Research (GA) -- SEP 01-05, 2019 -- Innsbruck, AUSTRIA
WOS: 000503772900343
ISSN: 0032-0943
Appears in Collections:Bioengineering / Biyomühendislik
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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