Please use this identifier to cite or link to this item:
https://hdl.handle.net/11147/4054
Title: | Production and characterization of water soluble CdSeTe based core/shell nanocrystals and their applications in bioimaging | Authors: | Özdemir, Seda | Advisors: | Özçelik, Serdar | Publisher: | İzmir Institute of Technology Izmir Institute of Technology |
Abstract: | In recent years, nanotechnology has become one of the most intensively studied fields. At the nanometer scale, materials have unique electrical, optical, magnetic and chemical properties. They can be used for a wide variety of applications such as electrooptical devices, tagging and medical applications. The goal of this study was to produce water-dispersible alloyed CdSexTe1-x semiconductor nanocrystals, which are suitable to interact with biomolecules. CdSexTe1-x nanocrystals were synthesized by a single step aqueous synthesis method. Monodisperse, CdSexTe1-x nanocrystals with zinc blende structure were obtained in water. Synthesized nanocrystals emit in the range from 528 nm to 620 nm. CdSexTe1-x nanocrystals have 17% photoluminescence quantum yield, after the CdS shell coating the photoluminescence quantum yield increased up to 22%. MTT test and Trypan Blue tests were used to evaluate the toxicity of CdSexTe1-x nanocrystals. MTT measurements reveal that the MCF7 cancer cells are not affected by the nanocrystals at any dosage and exposure condition, but lethal effects are determined at the concentration of 1.0ug/ml for the PC3 cells. The BEAS 2B cells are very sensitive to the nanocrystals and do not proliferate at concentration of 0.5ug/ml. Confocal microscopy studies show that the nanocrystals has ability to penetrate to the cytoplasm of cells. | Description: | Thesis (Master)--İzmir Institute of Technology, Chemistry, İzmir, 2009 Includes bibliographical references (leaves: 68-72) Text in English; Abstract: Turkish and English xiii, 72 leaves |
URI: | http://hdl.handle.net/11147/4054 |
Appears in Collections: | Master Degree / Yüksek Lisans Tezleri |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
T000227.pdf | MasterThesis | 7.71 MB | Adobe PDF | View/Open |
CORE Recommender
Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.