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https://hdl.handle.net/11147/12553| Title: | Peptıde targeted core cross-lınked mıcelles for dox delıvery to HER2 expressıng cancer cells | Authors: | Bayram, Nazende Nur Ulu, Gizem Tuğçe Gürdap, Seda İşoğlu, İsmail Alper Baran, Yusuf Dinçer İşoğlu, Sevil |
Keywords: | Breast cancer Core cross-linked micelles HER2 targeting |
Publisher: | Mary Ann Liebert | Abstract: | In this study, we prepared a novel targeted and extra stable micellar nanocarrier that can facilitate intracellular drug release. First, ((N-3-sulfopropyl-N, N-dimethylammonium)ethyl methacrylate was synthesized by RAFT polymerization, and it was followed by copolymerization of macroCTA with AEM in the presence of an aciddegradable cross-linker. Then, a peptide estimated by phage display for HER-2 recognition was incorporated into these core cross-linked micelles with carbodiimide reaction. | URI: | https://hdl.handle.net/11147/12553 |
| Appears in Collections: | Molecular Biology and Genetics / Moleküler Biyoloji ve Genetik WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| ten.tea.2022.29025.abstracts.pdf | Meeting Abstract | 49.2 kB | Adobe PDF | View/Open |
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