Food Engineering / Gıda Mühendisliği

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Citation - WoS: 4
Citation - Scopus: 7
Adding Pneumatic Compression Therapy in Lower Extremity Lymphedema Increases Compliance of Treatment, While Decreasing the Infection Rate
(Mary Ann Liebert, Inc, 2022) Soran, Atilla; Sezgin, Efe; Toktaş, Osman; Grassi, Ariel; Sezgin, Efe; 03.08. Department of Food Engineering; 03. Faculty of Engineering; 01. Izmir Institute of Technology
Background: Lymphedema (LE) is a chronic condition that requires lifelong treatment. Although pneumatic compression therapy (PCT) is one treatment option, current algorithms consider it as an adjunct to standard LE. The purpose of this study is to evaluate the importance of adapting PCT for lower extremity LE (LEL) in relation to patient compliance and rate of infection. Materials and Methods: Patients diagnosed with LEL were followed prospectively. Patient demographics, comorbidities, treatment modality, compliance, infection due to LE, and hospitalization were recorded. LEL patients with no-PCT were also recorded in the same time period to evaluate the treatment compliance and the need for physical therapy visits. The no-PCT group received the standard LE care, whereas the PCT group received the standard LE care plus a new-generation pneumatic compression device. Results: A total of 69 patients were enrolled in this study. The PCT group had 50 patients and no-PCT group had 19 patients. The PCT group had median 58.5 months of LE symptoms, while non-PCT patients had median 23 months of LE symptoms (p = 0.11). Infection rates decreased by 32% and hospitalizations due to infection decreased by 14% after PCT treatment had been initiated. Physical therapy needs decreased by 24% after PCT use. At median 18 months, follow-up compliance for PCT was 84%, but compliance for manual lymphatic drainage was almost half (53%) in no-PCT group. Conclusions: PCT leads to a decrease in infection rate, hospital admissions, and physical therapy (PT) visits in clinically significant LEL. Although there is no cost calculation in this study, it can be correlated to significant cost savings due to a reduction of infection and hospitalization and the need for PT visits. Adoption of PCT offers a superior value proposition to not only patients but also the health care system. Cost analysis should be followed.
Citation - WoS: 20
Citation - Scopus: 23
Antimicrobial Potential of Polylysine in Edible Films
(Japanese Society for Food Science and Technology, 2011) Uysal Ünalan, İlke; Korel, Figen; Arserim Uçar, Dılhun Keriman; Yemenicioğlu, Ahmet; Arcan, İskender; Korel, Figen; Yemenicioğlu, Ahmet; 03.08. Department of Food Engineering; 03. Faculty of Engineering; 01. Izmir Institute of Technology
The antimicrobial activity of edible films from whey proteins, alginate, zein and chitosan incorporated with polylysine (PL) and PL- ethylenediaminetetraacetic acid (Na 2EDTA) combination have been tested on different bacteria including Escherichia coli, Listeria innocua, Salmonella Typhimurium and Stapylococcus aureus. The PL-containing films of whey proteins, alginate and chitosan were effective on L. innocua, but had limited effect on E. coli. On the other hand, the PL-containing zein films showed good antimicrobial activity on both E. coli and L. innocua as well as on S. aureus. PL-Na 2EDTA combination also gave zein films effective on S. Typhimurium. The incorporation of PL alone or PL-Na 2EDTA combination did not cause any significant change in mechanical properties of zein films. Zein has a good potential to develop novel antimicrobial packaging materials incorporated with PL.
Citation - WoS: 3
Citation - Scopus: 5
Assessing the Impact of Non-Thermal and Thermal Treatment on the Shelf-Life of Onion Juice
(Czech Academy of Agricultural Sciences, 2018) Demir, Hande; Ünlütürk, Sevcan; Yıldız, Mustafa Kemal; Becerikli, İsmail; Ünlütürk, Sevcan; Kaya, Zehra; 03.08. Department of Food Engineering; 03. Faculty of Engineering; 01. Izmir Institute of Technology
Onion (Allium cepa L.) juice is a marinating agent for meat and fish marination and readily usable sauce for any meal that has onion in its formulation. This study aims to assess the microbiological and physicochemical changes in the onion juice processed by UV-C irradiation (0.5 mm sample depth, 30 min exposure time, 7.5 mW/cm(2) UV incident intensity) and conventional heat treatment (74.5 degrees C, 12 min) during its storage. Microbiological results showed processing by UV-C irradiation or heat treatment under optimum conditions extended the microbial shelf-life of untreated onion juice by minimum 6-times. Total colour change of heat-treated samples was lower than that of untreated and UV-C treated samples for 12 weeks. Also, pH, total titratable acidity, total soluble solids content, turbidity, NEBI and total phenolic content were monitored for 12 weeks. The results of this study will form scientific infrastructure for onion juice manufacturers to decide on the processing method with respect to its shelf-life.
Citation - WoS: 9
Citation - Scopus: 12
Capsaicin Emulsions: Formulation and Characterization
(Taylor and Francis Ltd., 2017-08) Akbaş, Elif; Söyler, Betül; Öztop, Mecit Halil
Oleoresin capsicum, the oil extract of chili pepper, is mainly composed of capsaicin. Capsaicin is a hydrophobic volatile compound exhibiting antimicrobial activity against various microorganisms. Capsaicin in the form of an emulsion-based carrier system could be a good alternative to enhance bioavailability and simultaneously to increase the shelf-life of food. In this study, capsaicin emulsions were formulated using three different surfactants (Tween 80, commercial soy lecithin, and sucrose monopalmitate/SMP). Effects of aqueous phase composition, pH, and heating the pre-homogenized dispersion were investigated. For characterization, NMR relaxometry, color, turbidity, and antioxidant activity experiments were conducted. Antimicrobial efficacies of the emulsions were also evaluated against Escherichia coli andStaphylococcus aureus. Mean particle sizes of emulsions with surfactants Tween 80, lecithin, and SMP were found to be 68.30, 582.63, and 50.10 nm, respectively. Lecithin-containing emulsions showed the highest antimicrobial activity against S. aureus with 4.60 log reduction, whereas the same effect was observed in Tween 80-containing emulsions against E. coli with 3.86 log reduction. Emulsions prepared with SMP showed the highest antioxidant activity with 0.482 mg DPPH/L emulsion. The formulated emulsions have the potential to be used in food industry as antimicrobial food grade solutions.
Citation - WoS: 5
Citation - Scopus: 5
Chemometric Analysis of Chemo-Optical Data for the Assessment of Olive Oil Blended With Hazelnut Oil
(Stazione Sperimentale per le Industrie, 2019-05) Kadiroğlu, Pınar; Korel, Figen; Korel, Figen; Pardo, Matteo; 03.08. Department of Food Engineering; 03. Faculty of Engineering; 01. Izmir Institute of Technology
The main objective of this study was to determine different hazelnut oil concentrations in extra virgin olive oil (EV00) belonging to different geographical regions inside Turkey using the combination of a SAW sensor based electronic nose (e-nose) and a machine vision system (MVS). We leveraged the oil characterisation given by the two easy-to-use and complementary experimental techniques through the adoption of conventional PCA for data exploration and random forests (RF) for supervised learning. The e-nose/MVS combination allows significantly better results both in adulteration detection independently of EVOO's geographical provenance and in EVO0 geographical provenance determination, independently of the adulteration level, with respect to the single characterisation method. RF analysis also produces feature ranking, permitting to shed light on which oils' characteristics influence the learning result. We found that EV00 geographical provenance discrimination is mainly due to yellowness and guaiacol content, while (E)-2-hexenal chiefly determines the prediction of the hazelnut level.
Citation - WoS: 2
Citation - Scopus: 3
Comparison of the Effects of Statins on A549 Nonsmall-Cell Lung Cancer Cell Line Lipids Using Fourier Transform Infrared Spectroscopy: Rosuvastatin Stands Out
(Wiley, 2021) Aksoy, Hatice Nurdan; Ceylan, Çağatay; Ceylan, Çağatay; 03.08. Department of Food Engineering; 03. Faculty of Engineering; 01. Izmir Institute of Technology
Statins are commonly prescribed antilipidemic and anticholesterol class of drugs. In addition to their major role, they have been found to have anticancer effects on in vitro, animal and clinical studies. The aim of this study was to investigate the effects of six different statins (rosuvastatin, pravastatin, simvastatin, lovastatin, fluvastatin, and atorvastatin) on A549 cancer cells lipids by Fourier transform infrared (FTIR) spectroscopy. Proliferation tests were carried out to detect the half-maximal inhibitory concentrations (IC50) of each statin on A549 cells. The IC50 values were 50 mu M for simvastatin, 150 mu M for atorvastatin and pravastatin, and 170 mu M for fluvastatin, 200 mu M for rosuvastatin and lovastatin on A549 cells. No correlation was found between the antiproliferative effects of the statins and lipid-lowering effect. The cells were treated with IC5, IC10, and IC50 values of each statins concentration and lipid extracts were compared using FTIR spectroscopy. The results indicated that different statins had different effects on the lipid content of A549 cells. The FTIR spectra of the lipid exctracts of statin-treated A549 cells indicated that the value of hydrocarbon chain length, unsaturation index, oxidative stress level, and phospholipid containing lipids increased except for rosuvastatin-treated A549 cells. In addition, rosuvastatin significantly lowered cholesterol ester levels. In conclusion, the contrasting effects of rosuvastatin should be further investigated.
Citation - WoS: 10
Citation - Scopus: 10
Detection of Listeria Species in Fresh Fish and Fish Market Environment by Ims Technique in Turkey
(Verlag M. und H. Schaper GmbH, 2011) Akkaya, Levent; Atabay, Halil İbrahim; Atabay, Halil İbrahim; Gök, Veli; Kara, Recep; 03.08. Department of Food Engineering; 03. Faculty of Engineering; 01. Izmir Institute of Technology
The incidence of Listeria spp. was investigated in fresh fish (n = 100) sold at retail markets and in the environmental and personnel samples (n = 100) obtained from several fish markets in Afyonkarahisar, Turkey by immunomagnetic separation technique. The fish samples analysed included anchovy, trout, carp and grey mullet (25 of each). Six (6 %) of the fish samples were found positive for Listeria spp. and the overall incidence of Listeria spp. was 10 % in the environmental and personnel samples. Three Listeria spp., Listeria monocytogenes, L. ivanovii, L. grayi were recovered from the samples examined. In addition, L. seeligeri from a fish sample and L. innocua from an environmental sample (box) were isolated. It was found that L. monocytogenes was only detected in fresh water fish with an incidence of 8 %. For the environmental samples, knives and refrigerators had the highest (20 %) and personnel samples had the least (5%) levels of contamination. It can be concluded that the fish sold at retail markets are moderately contaminated with various species of Listeria including L. monocytogenes, which may pose a risk for human health. The presence of these bacteria in environmental and personnel samples of fish markets is also an important possible sources of cross-contamination of the fish and other seafood. The results of this study indicate the necessity of the implementation of good hygiene and sanitary practices in order to prevent and/or reduce the contamination of fishery products by Listeria spp. at the retail level.
Determination of the Effects of Biomaterials on Human Peripheral Blood Mononuclear Cells (pbmc)
(IOS Press, 2002) Sudağıdan, Mert; Güneş, Hatice; Güneş, Hatice; Harsa, Hayriye Şebnem; Harsa, Şebnem; 04.03. Department of Molecular Biology and Genetics; 03.08. Department of Food Engineering; 03. Faculty of Engineering; 04. Faculty of Science; 01. Izmir Institute of Technology
Citation - WoS: 6
Citation - Scopus: 9
Determination of Volume of Alaska Pollock (theragra Chalcogramma) by Image Analysis
(Taylor and Francis Ltd., 2011-01) Balaban, Murat Ömer; Chombeau, Melanie; Gümüş, Bahar; Cırban, Dilşat
The objective of this study was to develop two methods to predict the volume of whole Alaska pollock and to compare the results with the experimentally measured volumes. One hundred fifty-five whole pollock, obtained from a Kodiak processor, were individually immersed in a graduated cylinder equipped with an outflow tube to catch the displaced water as a result of immersion. The weight of the water was recorded. Then the fish were placed in a light box equipped with a digital video camera, and the side view and top view recorded (2 images for each fish). A reference square of known surface area was placed by the fish. A cubic spline method to predict volume by integration of cross-sectional area slices based on the top and side views and an empirical equation using dimensional (length L, width W, depth D) measurements at three locations of the fish image were developed. The R 2 value for the correlation between the L × W × D versus measured volume was 0.987. The best R 2 for the correlation of the predicted volume by the cubic spline method versus the measured volume was 0.99. Image analysis can be used reliably to predict the volume of whole Alaska pollock. © Taylor & Francis Group, LLC.
Citation - WoS: 13
Citation - Scopus: 16
Dilute-Acid Hydrolysis of Apple, Orange, Apricot and Peach Pomaces as Potential Candidates for Bioethanol Production
(American Scientific Publishers, 2013-07) Üçüncü, Can; Özen, Fatma Banu; Tarı, Canan; Büyükkileci, Ali Oğuz; Demir, Hande; Tarı, Canan; Büyükkileci, Ali Oğuz; Özen, Banu; 03.08. Department of Food Engineering; 03. Faculty of Engineering; 01. Izmir Institute of Technology
Chemical composition of four selected fruit pomaces (agro-industrial wastes) was evaluated. The effect of temperature, time, acid concentration and solid:liquid (S:L) ratio on dilute-acid hydrolysis of selected pomaces were investigated using 24 factorial and central composite design and optimum hydrolysis conditions were determined. A preliminary study was initiated using apple hydrolysate and the fungus Tricoderma harzianum in order to explore and demonstrate their potential uses in bioethanol production. Chemical composition of pomaces was promising as fermentation media. The highest reducing sugar yield from the optimization step was 31%, 49%, 56% and 52% for apple, apricot, orange and peach pomaces, respectively under optimum hydrolysis conditions. Neither furfural nor hydroxmethylfurfural (HMF) were detected in hydrolysates. The highest bioethanol production (1.67 g/L) was obtained in 6 days in a non-static incubator using Tricoderma harzianum pregrown in minimal medium. It was demonstrated that selected pomaces holds potential for bioethanol production and can be eliminated without being potential waste problem to the environment, with economical return. Although, this work is an initial study in showing the potential of these pomaces and T. harzianum in bioethanol production, an extensive study on the optimization of fermentation parameters is recommended for further increase of bioethanol production. Copyright © 2013 American Scientific Publishers All rights reserved.
Citation - WoS: 5
Citation - Scopus: 3
Early Detection of Breast Cancer-Related Lymphedema: Accuracy of Indocyanine Green Lymphography Compared With Bioimpedance Spectroscopy and Subclinical Lymphedema Symptoms
(Mary Ann Liebert, 2023) Soran, Atilla; Sezgin, Efe; Bengur, Fuat Barış; Rodriguez, Wendy; Chroneos, Maria Z.; Sezgin, Efe; 03.08. Department of Food Engineering; 03. Faculty of Engineering; 01. Izmir Institute of Technology
Introduction: The reported incidences of breast cancer-related lymphedema (LE) affecting the arms vary greatly. Reason for this variability includes different diagnostic techniques used across studies. In the current study, we compared the accuracy of indocyanine green lymphography (ICG_L) and bioimpedance spectroscopy (BIS) in detecting LE before presentation of clinical signs.Methods and Results: Patients with no initial detectable signs of clinical LE of their arms after axillary lymph node dissection or removal of >5 lymph nodes on sentinel lymph node biopsy were included. Subclinical LE was defined as BIS values outside the normal range [(>= 7 units (or >10 units)] or a 7-unit (or 10 unit) change between two measurements. We tracked ICG_L and BIS measurements for 133 potentially affected arms (n = 123). ICG_L detected signs of lymphatic flow disruption in 63 arms (47%). Based on the BIS value of 7 units, 60 arms (45%) had values outside the normal range. When using ICG_L-identified LE cases as true positives, BIS had a 54% accuracy (area under the curve [AUC] = 0.54) in detecting LE. Accuracy was 61% for subclinical LE symptoms when compared with ICG_L (AUC = 0.62). Both BIS and subclinical LE symptoms had <0.70 AUC-receiver characteristic operator curve, suggesting that BIS and development of subclinical LE symptoms are not adequate for identifying patients with subclinical LE.Conclusion: ICG_L is a reliable diagnostic tool for detecting early signs of lymphatic flow disruption in subclinical LE. Utilizing ICG_L to diagnose subclinical LE followed by a personalized treatment plan may provide patients the best chance of preventing disease progression.
Citation - WoS: 2
Citation - Scopus: 2
Evaluation of Hemocytometer Parameters as Potential Biomarkers in Benign Multinodular Goiter and Papillary Thyroid Carcinoma
(Kowsar Publishing Company, 2017) Uysal, Erdal; Sezgin, Efe; Ceylan, Seyit Mehmet; Sezgin, Efe; Bakir, Hasan; Gurer, Ahmet Orhan; Aksoy, Basar; Bastemir, Mehmet; 03.08. Department of Food Engineering; 03. Faculty of Engineering; 01. Izmir Institute of Technology
Background: Hemocytometer parameters can be important biomarkers for some types of cancers and diseases. There is a need to evaluate their biomarker potential in thyroid diseases. Objectives: The current study aimed at contributing to potential biomarker researches to diagnose papillary thyroid carcinoma (PTC) and benign multinodular goiter (BMG), evaluate the role of these markers to determine the PTC characteristics and contribute to clarification of controversial issues. Methods: The study was designed as a retrospective observational study. The study included 389 patients who underwent total thyroidectomy at private Sani Konukoglu hospital (Sanko University, School of Medicine, Gaziantep, Turkey) due to BMG or PTC diagnosis from November 2011 to May 2017. The study subjects were divided into 3 groups. Groups 1, 2, and 3 were subjects with BMG, PTC, and the control, respectively. The comparisons were made among the groups in terms of hemocytometer parameters. In the group with the thyroid papillary carcinoma diagnosis, the relationship between the hemocytometer parameters and the bilateral tumor presence, single-sided multicentrite, and tumor diameter (size) were investigated. Results: Red cell distribution width (RDW) levels were 15.50 +/- 2.39, 15.68 +/- 2.16, and 12.5 +/- 1.51 in the BMG, PTC, and control groups, respectively. Mean platelet volumes (MPV) were 7.97 +/- 1.19, 8.05 +/- 1.20, and 7.23 +/- 1.39 in the BMG, PTC, and control groups, respectively. MPV and RDW values were significantly lower in group 3 compared with the groups 1 and 2 (P < 0.0001). Plateletcrit (PCT) values were 0.22 +/- 0.05, 0.23 +/- 0.06, and 0.19 +/- 0.05 in the BMG, PTC, and control groups, respectively. PCT was significantly lower in the group 3 compared with the groups 1 and 2 (P = 0.0001). In PTC group, no significant relationship was observed between any of the examined hematological parameters in terms of multicentric and bilateral tumor presence. Conclusions: RDW, MPV, haemoglobin content, and PCT were significantly higher in the BMG and PTC groups. This increase was not specific for either of the 2 groups. No significant difference was found between any of the hemocytometer parameters and the multicentricity and bilaterality of PTC. But, a possible correlation was observed between activated partial thromboplastin time (aPTT), hemoglobin content, and tumor size.
Citation - WoS: 2
Citation - Scopus: 4
Genotyping of Various Arcobacter Species Isolated From Domestic Geese by Randomly Amplified Polymorphic Dna (rapd) Analysis
(M. & H. Schaper, 2008-07) Atabay, Halil İbrahim; Atabay, Halil İbrahim; Ünver, Ahmet; Otlu, Salih; Kalaycıoğlu, Atila Taner; 03.08. Department of Food Engineering; 03. Faculty of Engineering; 01. Izmir Institute of Technology
The present study was undertaken to genotype Arcobacter (A.) butzleri, A. cryaerophilus and A. skirrowii isolates from domestic geese from three different flocks in Turkey. Fifteen Arcobacter isolates were analysed to determine the RAPD profiles based on the amplified DNA fragment patterns using a universal primer for genotyping. 7 A. cryaerophilus, 2 A. butzleri and 6 A. skirrowii isolates produced 6, 2 and 3 distinct profiles, respectively. The isolates of the same patterns originated from the same flocks. The findings of the present study may support previous reports of the existence of a large degree of heterogeneity among Arcobacter isolates. Observation of such levels of genetic diversity may suggest that there are multiple contamination sources in the environment and/or the determined genotypes may have undergone genetic rearrangements. This first report of genotyping of various Arcobacter species isolated from healthy geese is expected to improve the understanding of the ecology and epidemiology of this emerging pathogen.
Citation - WoS: 1
Citation - Scopus: 1
In Vitro Assessment of Food-Derived Bioaccessibility and Bioavailability in Bicameral Cell Culture System
(Türk Biyokimya Derneği, 2020) Özel Taşcı, Cansu; Güleç, Şükrü; Pilatin, Gözde; Edeer, Özgür; Güleç, Şükrü; 03.08. Department of Food Engineering; 03. Faculty of Engineering; 01. Izmir Institute of Technology
Background: Functional foods can help prevent metabolic diseases, and it is essential to evaluate functional characteristics of foods through in vitro and in vivo experimental approaches. Objective: We aimed to use the bicameral cell culture system combined with the in vitro digestion to evaluate glucose bioavailability. Materials and methods: Cake, almond paste, and pudding were modified by adding fiber and replacing sugar with sweeteners and polyols. Digestion process was modeled in test tubes. Rat enterocyte cells (IEC-6) were grown in a bicameral cell culture system to mimic the physiological characteristics of the human intestine. The glucose bioaccessibility and cellular glucose efflux were measured by glucose oxidase assay. Results and discussion: The glucose bioaccessibilities of modified foods were significantly lower (cake: 2.6 fold, almond paste: 9.2 fold, pudding 2.8 fold) than the controls. Cellular glucose effluxes also decreased in the modified cake, almond paste, and pudding by 2.2, 4, and 2 fold respectively compared to their controls. Conclusion: Our results suggest that combining in vitro enzymatic digestion with cell culture studies can be a practical way to test in vitro glucose bioaccessibility and bioavailability in functional food development.
Kinetic and Structural Characterization of Interaction Between Trypsin and Equisetum Arvense Extract
(Türk Biyokimya Derneği, 2014) Uslu, Mehmet Emin; Ceylan, Çağatay; Bayraktar, Oğuz; Bayraktar, Oğuz; Ceylan, Çağatay; 03.08. Department of Food Engineering; 03.02. Department of Chemical Engineering; 03. Faculty of Engineering; 01. Izmir Institute of Technology
Objective: In this study the inhibitory effect of E. arvense extract on trypsin activity and the effect of trypsin on E. arvense extract were studied. In addition the nature of the interaction between the extract and trypsin was investigated. Methods: The inhibitory effect ethanol extract of E. arvense on trypsin activity was determined using trypsin enzyme assay. The structural effects of the extract-trypsin interaction for the extract were analyzed by FTIR. Finally, the HPLC analyses were carried out to analyze the individual components of the extract and the supernatant and soluble precipitate phases. Results: E. arvense extract was found to decrease total percent activity of trypsin to 5% in 24 hour at 24 °C. FTIR analyses indicated that the interaction between trypsin and E. arvense extract caused changes in the structure and hydrogen bonding behavior and composition of the extract proteins. These interactions also caused the extract lipids to accumulate in the insoluble precipitate phase. Most of the phenolics remained in the supernatant phase enhancing the inactivation of trypsin. However, the precipitated compounds were shown to be of apolar in nature as shown in the HPLC chromatograms. Conclusion: The methods that were used showed that the high phenolic content of E. arvense was the main reason for the inhibition of trypsin enzyme activity by denaturing the enzyme.
Citation - WoS: 31
Citation - Scopus: 29
Lymphedema After Sentinel Lymph Node Biopsy: Who Is at Risk?
(Mary Ann Liebert, Inc., 2021) Işık, Arda; Sezgin, Efe; Soran, Atilla; Grasi, Ariel; Barry, Noran; Sezgin, Efe; 03.08. Department of Food Engineering; 03. Faculty of Engineering; 01. Izmir Institute of Technology
Aim: Sentinel lymph node biopsy (SLNB) is the accepted approach to stage the clinically negative axilla. The incidence of lymphedema (LE) after SLNB is about 5%. We hypothesize that patients undergoing axillary excision of >5 lymph nodes (LNs) are at increased risk of developing LE. Methods and Results: A single institution prospective breast cancer database was retrospectively reviewed from January 2013 to December 2017, to identify patients who underwent SLNB and were diagnosed with LE. Inclusion criteria was (1) de novo breast cancer, (2) SLNB in clinically node negative patients, and (3) no preoperative diagnosis LE of an extremity. Exclusion criteria was history of axillary lymph node dissection. Age, body mass index, tumor-node-metastasis status, surgery type, neoadjuvant or adjuvant chemotherapy, radiotherapy, and hormone therapy were analyzed. Of the 3325 patients identified, 2940 patients met the inclusion criteria and were included in the final analysis. Median follow-up time was 24 months. Forty-seven (2%) patients were diagnosed with LE, and nine patients (19%) had >5 LNs excised. LE was diagnosed in 3.7% of patients who had >5 LNs excised versus 1.4% of patients with <= 5 LNs excised. Incidence of LE was higher in patients with >5 LNs excision (p = 0.006). Conclusion: Our study showed that patients have a higher likelihood of developing LE when >5 LNs are excised.
Citation - WoS: 8
Citation - Scopus: 12
Odor Evaluation of Shrimp Treated With Different Chemicals Using an Electronic Nose and a Sensory Panel
(Taylor and Francis Ltd., 2007-08) Luzuriaga, Diego A.; Korel, Figen; Korel, Figen; Balaban, Murat Ömer; 03.08. Department of Food Engineering; 03. Faculty of Engineering; 01. Izmir Institute of Technology
An electronic nose with 12 conducting polymer sensors was used to measure odors of raw shrimp treated with different chemicals. Headless shell-on pink shrimp (Pandalus jordani) were treated with bleach (0, 25, 50, 100 and 200 ppm), phosphates (0, 2, 4 and 6% w/v) and sulfites (0, 0.75, 1.25 and 2% w/v) and stored at 2°C for 48 hours. Odors were evaluated by sensory panels and an electronic nose. Aerobic plate counts were performed. Discriminant function analysis was used as the pattern recognition technique to differentiate samples based on odors. Results showed that the electronic nose could discriminate differences in odor due to chemicals present in shrimp. The correct classification rates for bleach, phosphate and sulfite treated shrimp were 92.7, 95.8, and 99.2%, respectively.
Citation - WoS: 12
Citation - Scopus: 14
Prevalence, Virulence Characterization, and Genetic Relatedness of Listeria Monocytogenes Isolated From Chicken Retail Points and Poultry Slaughterhouses in Turkey
(Springer, 2019) Çoban, Ayşen; Molva, Çelenk; Pennone, Vincenzo; Sudağıdan, Mert; Molva, Çelenk; Jordan, Kieran; Aydın, Ali; 03.08. Department of Food Engineering; 03. Faculty of Engineering; 01. Izmir Institute of Technology
Listeria monocytogenes is one of the most important foodborne pathogens and is a causal agent of listeriosis in humans and animals. The aim of this study was to determine the prevalence, serogroups, antibiotic susceptibility, virulence factor genes, and genetic relatedness of L. monocytogenes strains isolated from 500 poultry samples in Turkey. The isolation sources of 103 L. monocytogenes strains were retail markets (n = 100) and slaughterhouses (n = 3). L. monocytogenes strains were identified as serogroups 1/2a-3a (75.7%, lineage I), 1/2c-3c (14.56%, lineage I), 1/2b-3b-7 (5.82%, lineage II), 4a-4c (2.91%, lineage III), and 4b-4d-4e (0.97%, lineage III). Most of the L. monocytogenes strains (93.2%) were susceptible to the antibiotics tested. PCR analysis indicated that the majority of the strains (95% to 100%) contained most of the virulence genes (hylA, plcA, plcB, prfA, mpl, actA, dltA, fri, flaA inlA, inlC, and inlJ). Pulsed-field gel electrophoresis (PFGE) demonstrated that there were 18 pulsotypes grouped at a similarity of >90% among the strains. These results indicate that it is necessary to prevent the presence of L. monocytogenes in the poultry-processing environments to help prevent outbreaks of listeriosis and protect public health.
Citation - WoS: 3
Citation - Scopus: 5
Production of Food Grade Ss-Galactosidase From Artisanal Yogurt Strains
(Taylor and Francis Ltd., 2010-01) Tarı, Canan; Harsa, Hayriye Şebnem; Üstok, Fatma Işık; Tarı, Canan; Harsa, Şebnem; 03.08. Department of Food Engineering; 03. Faculty of Engineering; 01. Izmir Institute of Technology
Superior artisanal isolates of thermophilic lactic acid bacteria producing high lactic acid and β-galactosidase were isolated from traditional Turkish yogurt samples from the Toros mountain region from a highly bio-diverse environment. A full factorial statistical design, with the factors of types of strains and medium formulations under static and agitation conditions, were applied to investigate the effects on β-galactosidase and lactic acid production. Streptococcus thermophilus 95/2 and Lactobacillus delbrueckii subsp. thermophilus 77 exhibited remarkable potential as promising starter culture candidates valuable to various applications in the dairy industry. The efficiency of cell disruption methods was investigated on the extraction of intracellular β-galactosidase enzyme. Lysozyme enzyme treatment was determined as the most effective method, which resulted in approximately 1.5 and 10 times higher enzyme activity than glass bead and homogenization treatment, respectively. © Taylor & Francis Group, LLC.
Citation - WoS: 12
Citation - Scopus: 18
Quality Evaluation of Alaska Pollock (theragra Chalcogramma) Roe by Image Analysis. Part I: Weight Prediction
(Taylor and Francis Ltd., 2012-01) Balaban, Murat Ömer; Chombeau, Melanie; Gümüş, Bahar; Cırban, Dilşat
Roe is an important product of the Alaska pollock (Theragra chalcogramma) industry. About 31% of the value for all pollock products comes from roe, yet roe is 5% of the weight of the fish. Currently, the size (weight), color, and maturity of the roe are subjectively evaluated. The objective of this study was to develop methods to predict the weight of Alaska pollock roe based on its view area from a camera and to differentiate between single and double roes. One hundred and forty-two pollock roes were picked from a processing line in a Kodiak, AK plant. Each roe was weighed, placed in a light box equipped with a digital video camera, images were taken at two different angles from one side, then turned over and presented at two different angles again (four images for each roe). A reference square of known surface area was placed by the roe. The following equations were used to fit the view area (X) versus weight (Y) data: linear, power, and second-order polynomial. Error rates for the classification of roes by weight decreased significantly when weight prediction equations for single and double roes were developed separately. A turn angle method, a box method, and a modified box method were tested to differentiate single and double roes by image analysis. Machine vision can accurately determine the weight of pollock roe. Practical Application Abstract: An image analysis method to accurately determine if pollock roe is a single or a double was developed. Then view area versus weight correlations were found for single and double roes that reduced incorrect weight classification rates to half that of human graders. © 2012 Copyright Taylor and Francis Group, LLC.

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