Now showing items 1-5 of 5
Characterization of the BETA1 gene, which might play a role in Beta vulgaris subsp. Maritima salt tolerance
Salinity stress has a negative impact on plant growth, which affects homeostasis and productivity. The uptake of nonessential salt ions changes the osmotic balance of the cell and causes dehydration. Higher plants develop ...
Proteomic changes during boron tolerance in barley (Hordeum vulgare) and the role of vacuolar proton-translocating ATPase subunit E
Boron is an essential micronutrient for plants and animals; however, it can be toxic when present at high concentrations. The purpose of this study was to understand the mechanisms of boron tolerance in the Turkish barley ...
Thiol peroxidase deficiency leads to increased mutational load and decreased fitness in saccharomyces cerevisiae
(Genetics Society of America, 2014-11)
Thiol peroxidases are critical enzymes in the redox control of cellular processes that function by reducing low levels of hydroperoxides and regulating redox signaling. These proteins were also shown to regulate genome ...
Functional characterization of new mutations in Wilson disease gene (ATP7B) using the yeast model
The Wilson disease gene, a copper transporting ATPase (Atp7b), is responsible for the sequestration of Cu into secretory vesicles, and this function is exhibited by the orthologous Ccc2p in the yeast. In this study, we ...
High-copy overexpression screening reveals PDR5 as the main doxorubicin resistance gene in yeast
(Public Library of Science, 2015-12)
Doxorubicin is one of the most potent anticancer drugs used in the treatment of various cancer types. The efficacy of doxorubicin is influenced by the drug resistance mechanisms and its cytotoxicity. In this study, we ...