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Apoptotic effects of resveratrol, a grape polyphenol, on imatinib-sensitive and resistant K562 chronic myeloid leukemia cells

Can, Geylani; Çakır, Zeynep; Kartal, Melis; Gündüz, Ufuk; Baran, Yusuf (International Institute of Anticancer Research, 2012-07)

To examine the antiproliferative and apoptotic effects of resveratrol on imatinib-sensitive and imatinib-resistant K562 chronic myeloid leukemia cells. Antiproliferative effects of resveratrol were determined by the ...

Macromolecular changes in nilotinib resistant k562 cells; An in vitro study by fourier transform infrared spectroscopy

Ceylan, Çağatay; Camgöz, Aylin; Baran, Yusuf (SAGE Publications, 2012-08)

Nilotinib is a second generation tyrosine kinase inhibitor which is used in both first and second line treatment of chronic myeloid leukemia (CML). In the present work, the effects of nilotinib resistance on K562 cells ...