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Synergistic apoptotic effects of bortezomib and methylstat on multiple myeloma cells
Background. In this study, we aimed to determine synergistic apoptotic and cytotoxic effects of methylstat and bortezomib on U266 and ARH77 multiple myeloma (MM) cells. Methods. Cytotoxic effects of the drugs were demonstrated ...
Apoptotic effects of non-edible parts of Punica granatum on human multiple myeloma cells
Multiple myeloma is of great concern since existing therapies are unable to cure this clinical condition. Alternative therapeutic approaches are mandatory, and the use of plant extracts is considered interesting. Punica ...
New indication for therapeutic potential of an old well-known drug (propranolol) for multiple myeloma
Purpose: Propranolol, a non-selective β-adrenergic receptor blocker, has been used for the treatment of the patients with hypertension for more than 50 years. There are several in vitro and in vivo evidences that β-adrenergic ...