Now showing items 1-6 of 6
Apoptotic effects of quercitrin on DLD-1 colon cancer cell line
Quercetin, which is the most abundant bioflavonoid compound, is mainly present in the glycoside form of quercitrin. Although different studies indicated that quercitrin is a potent antioxidant, the action of this compound ...
Therapeutic potential of apigenin, a plant flavonoid, for imatinib-sensitive and resistant chronic myeloid leukemia cells
Despite the presence of many therapeutic regimens like imatinib and other tyrosine kinase inhibitors, the development of resistance, intolerance, and side effects makes chronic myeloid leukemia (CML) therapy challenging. ...
Molecular mechanisms of quercitrin-induced apoptosis in non-small cell lung cancer
Background and Aims: Quercitrin (QR; quercetin-3-O-rhamnoside) has been used previously as an antibacterial agent and has been shown to inhibit the oxidation of low-density lipoproteins and prevent an allergic reaction. ...
New indication for therapeutic potential of an old well-known drug (propranolol) for multiple myeloma
Purpose: Propranolol, a non-selective β-adrenergic receptor blocker, has been used for the treatment of the patients with hypertension for more than 50 years. There are several in vitro and in vivo evidences that β-adrenergic ...
Anti-proliferative, apoptotic and signal transduction effects of hesperidin in non-small cell lung cancer cells
Purpose: Hesperidin, a glycoside flavonoid, is thought to act as an anti-cancer agent, since it has been found to exhibit both pro-apoptotic and anti-proliferative effects in several cancer cell types. The mechanisms ...
Investigation of potential anticarcinogenic effects of corilagin in lung cancer cells
(Marmara University, Institute of Health Sciences, 2019)
Objective: Lung cancer (LC) is the most extensive reason of cancer associated deaths in men and women in the world. LC categorizes into two main groups due to their molecular clinicopathological features and therapeutic ...