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An answer to colon cancer treatment by mesenchymal stem cell originated from adipose tissue
(Mashhad University of Medical Sciences, 2018-05)
Objective(s): Colon cancer is risen up with its complex mechanism that directly impacts on its treatment as well as its common prevalence. Mesenchymal stem cells (MSCs) have been considered as a therapeutic candidate for ...
The roles of epigenetic modifications of proapoptotic BID and BIM genes in imatinibresistant chronic myeloid leukemia cells
(Taylor & Francis, 2013-07)
In chronic myeloid leukemia (CML), epigenetic modifications such as promoter hypermethylation and inactive histone modification are known mechanisms of drug resistance. In our study, we investigated the roles of promoter ...
Effect of thioredoxin deletion and p53 cysteine replacement on human p53 activity in wild-type and thioredoxin reductase null yeast
(American Chemical Society, 2009)
Reporter gene transactivation by human p53 is inhibited in budding yeast lacking the TRR1 gene encoding thioredoxin reductase. To investigate the role of thioredoxin in controlling p53 activity, the level of reporter gene ...
Characterization of two genes encoding metal tolerance proteins from Beta vulgaris subspecies maritima that confers manganese tolerance in yeast
(Springer, 2013)
Manganese (Mn2+) is an essential micronutrient in plants. However increased Mn2+ levels are toxic to plant cells. Metal tolerance proteins (MTPs), member of cation diffusion facilitator protein (CDF) family, have important ...
In vitro antimicrobial activity screening of ethanol extract of Lavandula stoechas and investigation of its biochemical composition
(Hindawi Publishing, 2019)
The aim of this study was to test antimicrobial activity of ethanol extract of Lavandula stoechas against 22 bacteria and 1 yeast. Also, biochemical composition of the extract was investigated. A wide range of Gram-positive, ...
Conservation of gene function in the Solanaceae as revealed by comparative mapping of domestication traits in eggplant
(Genetics Society of America, 2002-08)
Quantitative trait loci (QTL) for domestication-related traits were identified in an interspecific F2 population of eggplant (Solanum linnaeanum × S. melongena). Although 62 quantitative trait loci (QTL) were identified ...
Mapping quantitative trait loci in inbred backcross lines of Lycopersicon pimpinellifolium (LA1589)
(National Research Council of Canada, 2002-11)
Although tomato has been the subject of extensive quantitative trait loci (QTLs) mapping experiments, most of this work has been conducted on transient populations (e.g., F2 or backcross) and few homozygous, permanent ...
A comparative genetic linkage map of eggplant (Solanum melongena) and its implications for genome evolution in the Solanaceae
(Genetics Society of America, 2002-08)
A molecular genetic linkage map based on tomato cDNA, genomic DNA, and EST markers was constructed for eggplant, Solanum melongena. The map consists of 12 linkage groups, spans 1480 cM, and contains 233 markers. Comparison ...
Evidence for a stabilizer element in the untranslated regions of Drosophila glutathione S-transferase D1 mRNA
(American Society for Biochemistry and Molecular Biology, 2002-09)
The neighboring genes gstD1 and gstD21 share 70% sequence identity, gstD1 encodes a 1,1,1-trichloro-2,2-bis-(P-chlorophenyl)ethane dehydrochlorinase; gstD21, a ligandin. Both of their mRNAs are inducible by pentobarbital ...
Purification and characterization of three members of the photolyase/cryptochrome family blue-light photoreceptors from vibrio cholerae
(American Society for Biochemistry and Molecular Biology, 2003-10)
The sequence of Vibrio cholerae genome revealed three genes belonging to the photolyase/cryptochrome blue-light photoreceptor family. The proteins encoded by the three genes were purified and characterized. All three ...
