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The roles of epigenetic modifications of proapoptotic BID and BIM genes in imatinibresistant chronic myeloid leukemia cells
(Taylor & Francis, 2013-07)
In chronic myeloid leukemia (CML), epigenetic modifications such as promoter hypermethylation and inactive histone modification are known mechanisms of drug resistance. In our study, we investigated the roles of promoter ...
Characterization of two genes encoding metal tolerance proteins from Beta vulgaris subspecies maritima that confers manganese tolerance in yeast
(Springer, 2013)
Manganese (Mn2+) is an essential micronutrient in plants. However increased Mn2+ levels are toxic to plant cells. Metal tolerance proteins (MTPs), member of cation diffusion facilitator protein (CDF) family, have important ...
In vitro antimicrobial activity screening of ethanol extract of Lavandula stoechas and investigation of its biochemical composition
(Hindawi Publishing, 2019)
The aim of this study was to test antimicrobial activity of ethanol extract of Lavandula stoechas against 22 bacteria and 1 yeast. Also, biochemical composition of the extract was investigated. A wide range of Gram-positive, ...
Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin
(Elsevier, 2018-04)
In this article, we report a small RNA data set obtained from human T cell acute leukemia Jurkat cells, which were treated with the universal apoptotic agent camptothecin. Based on the Annexin-V labeling pattern, we sorted ...
Health benefits and bioactive compounds of eggplant
(Elsevier, 2018-12)
Eggplant is a vegetable crop that is grown around the world and can provide significant nutritive benefits thanks to its abundance of vitamins, phenolics and antioxidants. In addition, eggplant has potential pharmaceutical ...
Molecular genetic diversity in the Origanum genus: EST-SSR and SRAP marker analyses of the 22 species in eight sections that naturally occur in Turkey
(Elsevier, 2018-11)
Origanum (L.) is a genus of herbaceous perennials with culinary and medicinal uses with many species found in the Mediterranean region. The taxonomic classification of species belonging to this genus has been studied using ...
Synthesis and Topoisomerase I inhibitory properties of klavuzon derivatives
(Elsevier, 2017-04)
Klavuzon is a naphthalen-1-yl substituted α,β-unsaturated δ-lactone derivative, and is one of the anti-proliferative members of this class of compounds. Asymmetric and racemic syntheses of novel α,β-unsaturated δ-lactone ...
Label-free quantitation, an extension to 2DB
(Springer, 2010-04)
Determining the differential expression of proteins under different conditions is of major importance in proteomics. Since mass spectrometry-based proteomics is often used to quantify proteins, several labelling strategies ...
Low-intensity vibrations normalize adipogenesis-induced morphological and molecular changes of adult mesenchymal stem cells
(SAGE Publications, 2017-02)
Bone marrow mesenchymal stem cells that are committed to adipogenesis were exposed daily to high-frequency low-intensity mechanical vibrations to understand molecular, morphological and ultrastructural adaptations to ...
5-Fluorouracil signaling through a calcium-calmodulin-dependent pathway is required for p53 activation and apoptosis in colon carcinoma cells
(Nature Publishing Group, 2013-09)
5-Fluorouracil (5-FU) is an anti-metabolite that is in clinical use for treatment of several cancers. In cells, it is converted into three distinct fluoro-based nucleotide analogs, which interfere with DNA synthesis and ...
