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Development of simple sequence repeat markers in hazelnut (Corylus avellana L.) by next-generation sequencing and discrimination of Turkish hazelnut cultivars
(Springer, 2018)
European hazelnut (Corylus avellana) is a diploid tree species and is widely used in confections. Hazelnuts are, to a large part, produced in Turkey with the cultivar "Tombul" widely grown in the Black Sea region. In this ...
MicroRNA categorization using sequence motifs and k-mers
(BioMed Central, 2017-03)
Background: Post-transcriptional gene dysregulation can be a hallmark of diseases like cancer and microRNAs (miRNAs) play a key role in the modulation of translation efficiency. Known pre-miRNAs are listed in miRBase, and ...
Newly developed SSR markers reveal genetic diversity and geographical clustering in spinach (Spinacia oleracea)
(Springer, 2017-08)
Spinach is a popular leafy green vegetable due to its nutritional composition. It contains high concentrations of vitamins A, E, C, and K, and folic acid. Development of genetic markers for spinach is important for diversity ...
Computational prediction of MicroRNAs from toxoplasma gondii potentially regulating the hosts' gene expression
(Elsevier, 2014-10)
MicroRNAs (miRNAs) were discovered two decades ago, yet there is still a great need for further studies elucidating their genesis and targeting in different phyla. Since experimental discovery and validation of miRNAs is ...
Categorization of species based on their microRNAs employing sequence motifs, information-theoretic sequence feature extraction, and k-mers
(Springer, 2017-12)
Background: Diseases like cancer can manifest themselves through changes in protein abundance, and microRNAs (miRNAs) play a key role in the modulation of protein quantity. MicroRNAs are used throughout all kingdoms and ...
Lithium protects against paraquat neurotoxicity by NRF2 activation and miR-34a inhibition in SH-SY5Y cells
(Frontiers Media, 2015-05-28)
Lithium is a mood stabilizing agent commonly used for the treatment of bipolar disorder. Here, we investigated the potential neuroprotective effect of lithium against paraquat toxicity and its underlying mechanisms in ...
Development of genomic simple sequence repeat markers in faba bean by next-generation sequencing
(Springer, 2017-02)
Faba bean (Vicia faba L.) is an important food legume crop with a huge genome. Development of genetic markers for faba bean is important to study diversity and for molecular breeding. In this study, we used Next Generation ...
Computational methods for microRNA target prediction
(Springer, 2014)
MicroRNAs (miRNAs) are important players in gene regulation. The final and maybe the most important step in their regulatory pathway is the targeting. Targeting is the binding of the miRNA to the mature RNA via the RNA-induced ...
Genomic simple sequence repeat markers reveal patterns of genetic relatedness and diversity in sesame
(Crop Science Society of America, 2015)
Sesame (Sesamum indicum L. syn. Sesamum orientale L.) is an orphan crop species with most molecular genetic research work done in the last decade. In this study, we used a pyrosequencing approach for the development of ...
Computational and bioinformatics methods for microRNA gene prediction
(Springer, 2014)
MicroRNAs (miRNAs) have attracted ever-increasing interest in recent years. Since experimental approaches for determining miRNAs are nontrivial in their application, computational methods for the prediction of miRNAs have ...
