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Determining the C-terminal amino acid of a peptide from MS/MS data
(Proteomass Scientific Society, 2013-12)
Proteomics is currently chiefly based on mass spectrometry (MS) which is the tool of choice to investigate proteins. Two computational approaches to derive the tandem mass spectrum precursor’s sequence are widely employed. ...
One step forward, two steps back; Xeno-MicroRNAs reported in breast milk are artifacts
(Public Library of Science, 2016-01)
Background: MicroRNAs (miRNAs) are short RNA sequences that guide post-transcriptional regulation of gene expression via complementarity to their target mRNAs. Discovered only recently, miRNAs have drawn a lot of attention. ...
Screening of damage induced by lead (Pb) in rye (Secale cereale L.) – a genetic and physiological approach
(Taylor & Francis, 2016-05-03)
The fields in which lead (Pb) finds application in the modern world have increased dramatically in recent years. As a consequence of this intensive utilization of Pb, its toxicity tends to pose more and more environmental ...
Protein based flushing related blood urea nitrogen effects on ovarian response, embryo recovery and embryo quality in superovulated ewes
(Elsevier, 2017-08)
The present study is the first report that evaluates effects of nutritional effects of flushing with differing diet crude protein ratios on blood urea nitrogen (BUN) levels, related some reproductive parameters and embryo ...
Prevalence of hepatitis B viral infection in Punjab province of Pakistan
(University of Punjab, 2017-08)
Hepatitis B viral (HBV) infection is a major health problem globally and more prevalent in Pakistan, and HBV. which is the main etiological agent of chronic hepatitis B, hepatocellular carcinoma and liver cirrhosis. A total ...
Antimicrobial activity and chemical composition screening of Anacyclus pyrethrum root
(Association of Pharmaceutical Teachers of India, 2017-07)
Medical herbs have many bioactive component and they are used in microbial treatment since ancient times. The resistance of pathogens to antibiotics became a critical problem, so researches for novel antimicrobial agents ...
Antimicrobial activity and chemical composition screening of Epilobium montanum root
(Association of Pharmaceutical Teachers of India, 2017-07)
Medical herbs have many bioactive component and they are used in microbial treatment since ancient time. The resistance of pathogen to antibiotic is became a critical problem, so novel antimicrobial agent related research ...
Effect of molecular architecture on cell interactions and stealth properties of PEG
(American Chemical Society, 2017-09)
PEGylation, covalent attachment of PEG to therapeutic biomolecules, in which suboptimal pharmacokinetic profiles limiting their therapeutic utility are of concern, is a widely applied technology. However, this technology ...
Enhancing tumor cell response to multidrug resistance with pH-sensitive quercetin and doxorubicin conjugated multifunctional nanoparticles
(Elsevier, 2017-08)
Classical chemotherapy uses chemotherapeutic agents as a mainstay of anticancer treatment. However, the development of multidrug resistance to chemotherapy limits the effectiveness of current cancer treatment. Nanosized ...
Newly developed SSR markers reveal genetic diversity and geographical clustering in spinach (Spinacia oleracea)
(Springer, 2017-08)
Spinach is a popular leafy green vegetable due to its nutritional composition. It contains high concentrations of vitamins A, E, C, and K, and folic acid. Development of genetic markers for spinach is important for diversity ...