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Bioactive Sphingolipids in response to chemotherapy: A scope on Leukemias
(Bentham Science Publishers, 2011-05)
Sphingolipids are major constituents of the cells with emerging roles in the regulation of cellular processes. Deregulation of sphingolipid metabolism is reflected as various pathophysiological conditions including metabolic ...
Novel agents targeting bioactive sphingolipids for the treatment of cancer
(Bentham Science Publishers, 2013-01)
Sphingolipids are a class of lipids that have important functions in a variety of cellular processes such as, differentiation, proliferation, senescence, apoptosis and chemotherapeutic resistance. The most widely studied ...
Therapeutic potential of targeting ceramide/glucosylceramide pathway in cancer
Sphingolipids including ceramides and its derivatives such as ceramide-1-phosphate, glucosylceramide (GlcCer), and sphingosine-1-phosphate are essential structural components of cell membranes. They now recognized as novel ...