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Relative protein quantitation with post translational modifications in mass spectrometry based proteomics
Mass spectrometry has become the tool of choice for most investigations in proteomics. Identification of proteins from complex mixtures has long been achieved and is now routinely used in countless high throughput studies. ...
Ranking tandem mass spectra: And the impact of database size and scoring function on peptide spectrum matches
Proteomics is currently driven by mass spectrometry. For the analysis of tandem mass spectra many computational algorithms have been proposed. There are two approaches, one which assigns a peptide sequence to a tandem mass ...