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Removing contamination from genomic sequences based on vector reference libraries
DNA is often sequenced after being cloned into a vector since this provides the possibility for using standard primers and removes the need to develop custom primers. In this way a certain amount of vector is sequenced ...
De novo markup language, a standard to represent de novo sequencing results from MS/MS data
Proteomics is the study of the proteins that can be derived from a genome. For the identification and sequencing of proteins, mass spectrometry has become the tool of choice. Within mass spectrometry-based proteomics, ...
Existing bioinformatics tools for the quantitation of post-translational modifications
Mass spectrometry (MS)-based proteomics, by itself, is a vast and complex area encompassing various mass spectrometers, different spectra, and search result representations. When the aim is quantitation performed in different ...