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Proteasome inhibitor bortezomib increases radiation sensitivity in androgen independent human prostate cancer cells
Objectives: To investigate the effects of a strong proteasome inhibitor, bortezomib alone or in combination with radiotherapy on androgen-independent DU145 human prostate cancer cells. Proteasomes play important roles in ...
IRF6 is involved in the regulation of cell proliferation and transformation in MCF10A cells downstream of notch signaling
(Public Library of Science, 2015-07-10)
IRF6, a member of Interferon Regulatory Factors (IRF) family, is involved in orofacial and epidermal development. In breast cancer cell lines ectopic expression of IRF6 reduces cell numbers suggesting a role as negative ...