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Characterization of the BETA1 gene, which might play a role in Beta vulgaris subsp. Maritima salt tolerance 

Uysal, Özge; Çakıroğlu, Çiğdem; Koç, Ahmet; Karakaya, Hüseyin Çağlar (TÜBİTAK, 2017)
Salinity stress has a negative impact on plant growth, which affects homeostasis and productivity. The uptake of nonessential salt ions changes the osmotic balance of the cell and causes dehydration. Higher plants develop ...
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Genome-wide identification of genes that play a role in boron stress response in yeast 

Uluışık, İrem; Kaya, Alaattin; Ünlü, Ercan Selçuk; Avşar, Kadir; Karakaya, Hüseyin Çağlar; Yalçın, Talat; Koç, Ahmet (Elsevier BV., 2011-02)
Boron is an essential micronutrient for plants and it is either necessary or beneficial for animals. Studies identified only few genes related to boron metabolism thus far and details of how boron is imported into cells ...
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Characterization of two genes encoding metal tolerance proteins from Beta vulgaris subspecies maritima that confers manganese tolerance in yeast 

Erbaşol, Işıl; Bozdağ, Gönensin Ozan; Koç, Ahmet; Pedas, Pia; Karakaya, Hüseyin Çağlar (Springer, 2013)
Manganese (Mn2+) is an essential micronutrient in plants. However increased Mn2+ levels are toxic to plant cells. Metal tolerance proteins (MTPs), member of cation diffusion facilitator protein (CDF) family, have important ...
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Compartmentalization and regulation of mitochondrial function by methionine sulfoxide reductases in yeast 

Kaya, Alaattin; Koç, Ahmet; Lee, Byung Cheon; Fomenko, Dmitri E.; Rederstorff, Mathieu; Krol, Alain; Lescure, Alain; Gladyshev, Vadim N. (American Chemical Society, 2010-10)
Elevated levels of reactive oxygen species can damage proteins. Sulfur-containing amino acid residues, cysteine and methionine, are particularly susceptible to such damage. Various enzymes evolved to protect proteins or ...
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Identification of respiratory chain gene mutations that shorten replicative life span in yeast 

Hacıoğlu, Elise; Demir, Ayşe Banu; Koç, Ahmet (Elsevier, 2012-02)
Aging is the progressive accumulation of alterations in cells that elevates the risk of death. The mitochondrial theory of aging postulates that free radicals produced by the mitochondrial respiratory system contribute to ...
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Evidence for the presence of a second electron donor for the cytoplasmic thioredoxins in the yeast Saccharomyces cerevisiae 

Koç, Ahmet; Karakaya, Hüseyin Çağlar; Ünlü, Ercan Selçuk (TÜBİTAK, 2006)
In yeast, the cytoplasmic thioredoxin system is composed of NADPH, thioredoxin reductase-1 (TRR1) and 2 thioredoxin genes (TRX1, TRX2). In this study, using yeast knockout mutants for TRR1, TRX1 and TRX2 genes, the role ...
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The roles of thiol oxidoreductases in yeast replicative aging 

Hacıoğlu, Elise; Esmer, Işıl; Fomenko, Dmitri E.; Gladyshev, Vadim N.; Koç, Ahmet (Elsevier, 2010-11)
Thiol-based redox reactions are involved in the regulation of a variety of biological functions, such as protection against oxidative stress, signal transduction and protein folding. Some proteins involved in redox regulation ...
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Checkpoint deficient rad53-11 yeast cannot accumulate dNTPs in response to DNA damage 

Koç, Ahmet; Merrill, Gary F. (Elsevier, 2007-02)
Deoxyribonucleotide pools are maintained at levels that support efficient and yet accurate DNA replication and repair. Rad53 is part of a protein kinase regulatory cascade that, conceptually, promotes dNTP accumulation in ...
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Identification of a novel system for boron transport: Atr1 is a main boron exporter in yeast 

Kaya, Alaattin; Karakaya, Hüseyin Çağlar; Fomenko, Dmitri E.; Gladyshev, Vadim N.; Koç, Ahmet (American Society for Microbiology, 2009-07)
Boron is a micronutrient in plants and animals, but its specific roles in cellular processes are not known. To understand boron transport and functions, we screened a yeast genomic DNA library for genes that confer resistance ...
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Characterization of a cDNA from Beta maritima that confers nickel tolerance in yeast 

Bozdaǧ, Gönensin Ozan; Kaya, Alaattin; Koç, Ahmet; Noll, Gundula A.; Prüfer, Dirk; Karakaya, Hüseyin Çaǧlar (Elsevier, 2014-04)
Nickel is an essential micronutrient due to its involvement in many enzymatic reactions as a cofactor. However, excess of this element is toxic to biological systems. Here, we constructed a cDNA library from Beta maritima ...
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Koç, Ahmet (11)
Karakaya, Hüseyin Çağlar (6)Kaya, Alaattin (4)Fomenko, Dmitri E. (3)Gladyshev, Vadim N. (3)Bozdağ, Gönensin Ozan (2)Hacıoğlu, Elise (2)Uluışık, İrem (2)Ünlü, Ercan Selçuk (2)Avşar, Kadir (1)... View MoreSubject
Yeast (11)
Boron (3)Saccharomyces cerevisiae (3)Aging (2)Boric acid (2)Mitochondria (2)Amino acids (1)Antioxidant (1)ATR1 (1)ATR1 gene (1)... View MorePublication Typearticle (11)Languageeng (11)Publication CategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı (9)Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı (2)Access Type
info:eu-repo/semantics/openAccess (11)
Date Issued2010 - 2017 (8)2006 - 2009 (3)Has File(s)Yes (11)

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