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Functional analysis of free methionine-R-sulfoxide reductase from saccharomyces cerevisiae

Le, Dung Tien; Lee, Byung Cheon; Marino, Stefano M.; Zhang, Yan; Fomenko, Dmitri E.; Kaya, Alaattin; Hacıoğlu, Elise; Kwak, Geun-Hee; Koç, Ahmet; Kim, Hwa-Young; Gladyshev, Vadim N. (American Society for Biochemistry and Molecular Biology, 2009-02)

Methionine sulfoxide reductases (Msrs) are oxidoreductases that catalyze thiol-dependent reduction of oxidized methionines. MsrA and MsrB are the best known Msrs that repair methionine S-sulfoxide (Met-S-SO) and ...

Evidence for the presence of a second electron donor for the cytoplasmic thioredoxins in the yeast Saccharomyces cerevisiae

Koç, Ahmet; Karakaya, Hüseyin Çağlar; Ünlü, Ercan Selçuk (TÜBİTAK, 2006)

In yeast, the cytoplasmic thioredoxin system is composed of NADPH, thioredoxin reductase-1 (TRR1) and 2 thioredoxin genes (TRX1, TRX2). In this study, using yeast knockout mutants for TRR1, TRX1 and TRX2 genes, the role ...