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The roles of epigenetic modifications of proapoptotic BID and BIM genes in imatinibresistant chronic myeloid leukemia cells

Bozkurt, Süreyya; Özkan, Tülin; Özmen, Füsun; Baran, Yusuf; Sunguroǧlu, Asuman; Kansu, Emin (Taylor & Francis, 2013-07)

In chronic myeloid leukemia (CML), epigenetic modifications such as promoter hypermethylation and inactive histone modification are known mechanisms of drug resistance. In our study, we investigated the roles of promoter ...