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Data mining for microrna gene prediction: On the impact of class imbalance and feature number for microrna gene prediction
MicroRNAs (miRNAs) are small, non-coding RNAs which are involved in the posttranscriptional modulation of gene expression. Their short (18-24) single stranded mature sequences are involved in targeting specific genes. It ...
Ranking tandem mass spectra: And the impact of database size and scoring function on peptide spectrum matches
Proteomics is currently driven by mass spectrometry. For the analysis of tandem mass spectra many computational algorithms have been proposed. There are two approaches, one which assigns a peptide sequence to a tandem mass ...
Comparison of four Ab initio MicroRNA prediction tools
MicroRNAs are small RNA sequences of 18-24 nucleotides in length, which serve as templates to drive post transcriptional gene silencing. The canonical microRNA pathway starts with transcription from DNA and is followed by ...