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Gene reporter assay to validate microRNA targets in drosophila S2 cells
(Humana Press, 2014)
Bioinformatics programs have helped tremendously in identifying the targets of microRNAs, which are small noncoding RNAs that regulate gene expression posttranscriptionally. However, the partial complementarity between ...
Computational methods for microRNA target prediction
(Springer, 2014)
MicroRNAs (miRNAs) are important players in gene regulation. The final and maybe the most important step in their regulatory pathway is the targeting. Targeting is the binding of the miRNA to the mature RNA via the RNA-induced ...
Computational and bioinformatics methods for microRNA gene prediction
(Springer, 2014)
MicroRNAs (miRNAs) have attracted ever-increasing interest in recent years. Since experimental approaches for determining miRNAs are nontrivial in their application, computational methods for the prediction of miRNAs have ...
Machine learning methods for microRNA gene prediction
(Humana Press, 2014)
MicroRNAs (miRNAs) are single-stranded, small, noncoding RNAs of about 22 nucleotides in length, which control gene expression at the posttranscriptional level through translational inhibition, degradation, adenylation, ...
Intersection of MicroRNA and gene regulatory networks and their implication in cancer
(Bentham Science Publishers, 2014-09)
MicroRNAs (miRNAs) have attracted heightened attention for their role as post-transcriptional regulators of gene expression. It has become clear that miRNAs can both up- and downregulate protein expression. According to ...
Master regulators of posttranscriptional gene expression are subject to regulation
(Springer, 2014)
MicroRNAs (miRNAs) are small noncoding RNAs of 17-25 nt in length that control gene expression posttranscriptionally. As master regulators of posttranscriptional gene expression, miRNAs themselves are subject to tight ...
