Search
Now showing items 1-10 of 39
Effect of molecular architecture on cell interactions and stealth properties of PEG
(American Chemical Society, 2017-09)
PEGylation, covalent attachment of PEG to therapeutic biomolecules, in which suboptimal pharmacokinetic profiles limiting their therapeutic utility are of concern, is a widely applied technology. However, this technology ...
Synthesis and Topoisomerase I inhibitory properties of klavuzon derivatives
(Elsevier, 2017-04)
Klavuzon is a naphthalen-1-yl substituted α,β-unsaturated δ-lactone derivative, and is one of the anti-proliferative members of this class of compounds. Asymmetric and racemic syntheses of novel α,β-unsaturated δ-lactone ...
Low-intensity vibrations normalize adipogenesis-induced morphological and molecular changes of adult mesenchymal stem cells
(SAGE Publications, 2017-02)
Bone marrow mesenchymal stem cells that are committed to adipogenesis were exposed daily to high-frequency low-intensity mechanical vibrations to understand molecular, morphological and ultrastructural adaptations to ...
Mineral nutrient acquisition by cotton cultivars grown under salt stress
(Taylor & Francis, 2017-04)
Physiological responses were investigated in two cotton cultivars grown at various concentrations of sodium chloride (NaCl) in order to determine the degree of the tolerance of the cultivars to salt stress and understand ...
On the performance of pre-microRNA detection algorithms
(Nature Publishing Group, 2017-12)
MicroRNAs are crucial for post-transcriptional gene regulation, and their dysregulation has been associated with diseases like cancer and, therefore, their analysis has become popular. The experimental discovery of miRNAs ...
Protective effects of polyamines against UV-A and UV-B illumination in Physcia semipinnata thalli
(Institute of Botany and Botanical Garden Jevremovac, 2017)
The damage to DNA induced by UV-A and UV-B and protective effects of the polyamines putrescine (put), spermidine (spd) and spermine (spm) were investigated on the lichen Physcia semipinnata in the present study. Our results ...
CRM1 inhibitory and antiproliferative activities of novel 4′-alkyl substituted klavuzon derivatives
(Elsevier, 2017)
Klavuzons are 6-(naphthalen-1-yl) substituted 5,6-dihydro-2H-pyran-2-one derivatives showing promising antiproliferative activities in variety of cancer cell lines. In this work, racemic syntheses of nine novel 4′-alkyl ...
MicroRNA categorization using sequence motifs and k-mers
(BioMed Central, 2017-03)
Background: Post-transcriptional gene dysregulation can be a hallmark of diseases like cancer and microRNAs (miRNAs) play a key role in the modulation of translation efficiency. Known pre-miRNAs are listed in miRBase, and ...
Newly developed SSR markers reveal genetic diversity and geographical clustering in spinach (Spinacia oleracea)
(Springer, 2017-08)
Spinach is a popular leafy green vegetable due to its nutritional composition. It contains high concentrations of vitamins A, E, C, and K, and folic acid. Development of genetic markers for spinach is important for diversity ...
Relationship between geographical origin, seed size and genetic diversity in faba bean (Vicia faba L.) as revealed by SSR markers
(Springer, 2017-10)
Faba bean (Vicia faba L.) is an important legume species because of its high protein and starch content. Broad bean can be grown in different climatic conditions and is an ideal rotation crop because of the nitrogen fixing ...
