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Roles of ceramide synthase and ceramide clearence genes in nilotinib-induced cell death in chronic myeloidleukemia cells

Camgöz, Aylin; Gençer, Emel Başak; Ural, Ali Uǧur; Avcu, Ferit; Baran, Yusuf (Informa Healthcare, 2011-08)

In this study, we aimed to increase the sensitivity of human K562 and Meg-01 chronic myeloid leukemia (CML) cells to nilotinib by targeting bioactive sphingolipids, in addition to investigating the roles of ceramide ...