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A novel mechanism of dasatinib-induced apoptosis in chronic myeloid leukemia; Ceramide synthase and ceramide clearance genes

Gencer, Emel Başak; Ural, Ali Uǧur; Avcu, Ferit; Baran, Yusuf (Springer, 2011-11)

Sphingolipids are bioeffector molecules that control various aspects of cell growth, proliferation, apoptosis, and drug resistance. Ceramides, the central molecule of sphingolipid metabolism, are inducer of apoptosis and ...