Now showing items 1-4 of 4
Relative protein quantitation with post translational modifications in mass spectrometry based proteomics
Mass spectrometry has become the tool of choice for most investigations in proteomics. Identification of proteins from complex mixtures has long been achieved and is now routinely used in countless high throughput studies. ...
PGMiner: Complete proteogenomics workflow; from data acquisition to result visualization
In parallel with the development of nucleotide sequencing an equally important interest in further describing the sequence in terms of function arose and the latter represents the current bottleneck in the overall research ...
Algorithms for the de novo sequencing of peptides from tandem mass spectra
(Taylor & Francis, 2011-10)
Proteomics is the study of proteins, their time- and location-dependent expression profiles, as well as their modifications and interactions. Mass spectrometry is useful to investigate many of the questions asked in ...
Ranking tandem mass spectra: And the impact of database size and scoring function on peptide spectrum matches
Proteomics is currently driven by mass spectrometry. For the analysis of tandem mass spectra many computational algorithms have been proposed. There are two approaches, one which assigns a peptide sequence to a tandem mass ...