Now showing items 1-2 of 2
IRF6 is involved in the regulation of cell proliferation and transformation in MCF10A cells downstream of notch signaling
(Public Library of Science, 2015-07-10)
IRF6, a member of Interferon Regulatory Factors (IRF) family, is involved in orofacial and epidermal development. In breast cancer cell lines ectopic expression of IRF6 reduces cell numbers suggesting a role as negative ...
Progesterone/RANKL is a major regulatory axis in the human breast
(American Association for the Advancement of Science, 2013-04)
Estrogens and progesterones are major drivers of breast development but also promote carcinogenesis in this organ. Yet, their respective roles and the mechanisms underlying their action in the human breast are unclear. ...