Now showing items 1-3 of 3
Novel agents targeting bioactive sphingolipids for the treatment of cancer
(Bentham Science Publishers, 2013-01)
Sphingolipids are a class of lipids that have important functions in a variety of cellular processes such as, differentiation, proliferation, senescence, apoptosis and chemotherapeutic resistance. The most widely studied ...
Therapeutic applications of bioactive sphingolipids in hematological malignancies
Sphingolipids are sphingosine-based lipid molecules that have important functions in cellular signal transduction and in a variety of cellular processes including proliferation, differentiation, programmed cell death ...
Molecular mechanisms of drug resistance and its reversal in cancer
(Taylor & Francis, 2016-07)
Chemotherapy is the main strategy for the treatment of cancer. However, the main problem limiting the success of chemotherapy is the development of multidrug resistance. The resistance can be intrinsic or acquired. The ...